Now showing items 1-2 of 2

    • Associations of urinary orosomucoid, N-acetyl-β-D-glucosaminidase, and albumin with blood pressure and hypertension during 7 years of follow-up. The Tromsø Study 

      Brobak, Karl Marius; Andreassen, Runa Marie; Melsom, Toralf; Høieggen, Aud; Norvik, Jon Viljar; Solbu, Marit Dahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-03)
      Purpose: Subclinical chronic kidney disease is known to exacerbate hypertension and progression of kidney damage. In order to initiate timely interventions, early biomarkers for this vicious circle are needed. Our aim was to describe the cross-sectional associations of urinary orosomucoid and urinary N-acetyl-b-D-glucosaminidase (NAG) with blood pressure and the longitudinal associations of urinary ...
    • Detection of Nonadherence to Antihypertensive Treatment by Measurements of Serum Drug Concentrations 

      Bergland, Ola Undrum; Halvorsen, Lene Vernås; Søraas, Camilla Lund; Hjørnholm, Ulla; Kjær, Vibeke Norheim; Rognstad, Stine; Brobak, Karl Marius; Aune, Arleen; Olsen, Eirik; Fauchald, Ylva; Heimark, Sondre; Thorstensen, Christian W; Liestøl, Knut; Solbu, Marit Dahl; Gerdts, Eva; Mo, Rune; Rostrup, Morten; Kjeldsen, Sverre; Høieggen, Aud; Opdal, Mimi Stokke; Fadl Elmula, Fadl Elmula M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-19)
      Nonadherence to drugs is a challenge in hypertension treatment. We aimed to assess the prevalence of nonadherence by serum drug concentrations compared with 2 indirect methods and relate to the prescribed drug regimens in a nationwide multicenter study. Five hundred fifty patients with hypertension using ≥2 antihypertensive agents participated. We measured concentrations of 23 antihypertensive drugs ...