Now showing items 1-3 of 3

    • Anatomical variations in the circle of Willis are associated with increased odds of intracranial aneurysms: The Tromsø study 

      Hindenes, Lars Bakke; Ingebrigtsen, Tor; Isaksen, Jørgen Gjernes; Håberg, Asta; Johnsen, Liv-Hege; Herder, Marit; Mathiesen, Ellisiv B.; Vangberg, Torgil Riise (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-25)
      Purpose: Studies on patients suggest an association between anatomical variations in the Circle of Willis (CoW) and intracranial aneurysms (IA), but it is unclear whether this association is present in the general population. In this cross-sectional population study, we investigated the associations between CoW anatomical variations and IA.<p> <p>Methods: We included 1667 participants from a ...
    • An incomplete Circle of Willis is not a risk factor for white matter hyperintensities: The Tromsø Study 

      Hindenes, Lars Bakke; Håberg, Asta Kristine; Mathiesen, Ellisiv B; Vangberg, Torgil Riise (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-11)
      <p><i>Objective - </i>The Circle of Willis (CoW) is often underdeveloped or incomplete, leading to suboptimal blood supply to the brain. As hypoperfusion is thought to play a role in the aetiology of white matter hyperintensities (WMH), the objective of this study was to assess whether incomplete CoW variants were associated with increased WMH volumes compared to the complete CoW. <p><i>Methods - ...
    • Variations in the Circle of Willis in a large population sample using 3D TOF angiography: The Tromsø Study 

      Hindenes, Lars Bakke; Håberg, Asta; Johnsen, Liv-Hege; Mathiesen, Ellisiv B.; David, Robben; Vangberg, Torgil Riise (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-03)
      The main arteries that supply blood to the brain originate from the Circle of Willis (CoW). The CoW exhibits considerable anatomical variations which may have clinical importance, but the variability is insufficiently characterised in the general population. We assessed the anatomical variability of CoW variants in a community-dwelling sample (N = 1,864, 874 men, mean age = 65.4, range 40–87 years), ...