• Effect of Colonoscopy Screening on Risks of Colorectal Cancer and Related Death 

      Bretthauer, Michael; Løberg, Magnus; Wieszczy, Paulina; Kalager, Mette; Emilsson, Louise; Garborg, Kjetil Kjeldstad; Rupinski, Maciej; Dekker, Evelien; Spaander, Manon; Bugajski, Marek; Holme, Øyvind; Zauber, Ann G.; Pilonis, Nastazja D.; Mróz, Andrzej; Kuipers, Ernst J.; Shi, Joy; Hernán, Miguel A.; Adami, Hans Olov; Regula, Jaroslaw; Hoff, Geir; Kamiński, Michał Filip (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-27)
      <p><i>Background:</i> Although colonoscopy is widely used as a screening test to detect colorectal cancer, its effect on the risks of colorectal cancer and related death is unclear. <p><i>Methods:</i> We performed a pragmatic, randomized trial involving presumptively healthy men and women 55 to 64 years of age drawn from population registries in Poland, Norway, Sweden, and the Netherlands between ...
    • The inflammatory response is related to circulatory failure after out-of-hospital cardiac arrest: A prospective cohort study 

      Langeland, Halvor Johannes Breivik; Damås, Jan Kristian; Mollnes, Tom Eirik; Ludviksen, Judith K; Ueland, Thor; Michelsen, Annika Elisabet; Løberg, Magnus; Bergum, Daniel; Nordseth, Trond; Skjærvold, Nils Kristian; Klepstad, Pål (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-24)
      Background: Whole body ischemia and reperfusion injury after cardiac arrest leads to the massive inflammation clinically manifested in the post-cardiac arrest syndrome. Previous studies on the inflammatory effect on circulatory failure after cardiac arrest have either investigated a selected patient group or a limited part of the inflammatory mechanisms. We examined the association between cardiac ...
    • Mortality in Norway and Sweden during the COVID-19 pandemic 

      Juul, Frederik E.; Jodal, Henriette C.; Barua, Ishita; Refsum, Erle; Olsvik, Ørjan; Helsingen, Lise M.; Løberg, Magnus; Bretthauer, Michael; Kalager, Mette; Emilsson, Louise (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-05)
      Background: Norway and Sweden are similar countries in terms of socioeconomics and health care. Norway implemented extensive COVID-19 measures, such as school closures and lockdowns, whereas Sweden did not. Aims: To compare mortality in Norway and Sweden, two similar countries with very different mitigation measures against COVID-19. <p> <p>Methods: Using real-world data from national registries, ...
    • A novel intragastric balloon for treatment of obesity and type 2 diabetes. A two-center pilot trial 

      Tønnesen, Christer Julseth; Hjelmesæth, Jøran Sture; Hofsø, Dag; Tonstad, Serena; Hertel, Jens Kristoffer; Heggen, Eli; Johnson, Line Kristin; Mathisen, Tor Erik; Kalager, Mette; Wieszczy, Paulina; Medhus, Asle Wilhelm; Løberg, Magnus; Aabakken, Lars; Bretthauer, Michael (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-29)
      Background and aims: Obesity with type-2 diabetes is a global challenge. Lifestyle interventions have limited effect for most patients. Bariatric surgery is highly effective, but resource-demanding, invasive and associated with serious complications. Recently, a new intragastric balloon was introduced, not requiring endoscopy for placement or removal (Elipse™, Allurion Inc., Natick, MA). The balloon ...
    • A pilot study of implementation of endoscopic sleeve gastroplasty (ESG) in Norway 

      Tønnesen, Christer Julseth; Hjelmesæth, Jøran Sture; Aabakken, Lars; Lund, Randi Størdal; Johnson, Line Kristin; Hertel, Jens Kristoffer; Kalager, Mette; Løberg, Magnus; Bretthauer, Michael (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-26)
      Background and aim - Bariatric surgery is the most effective treatment for obesity but is invasive and associated with serious complications. Endoscopic sleeve gastroplasty (ESG) is a less invasive weight loss procedure to reduce the stomach volume by full-thickness sutures. ESG has been adopted in many countries, but implementation at Scandinavian centres has not yet been documented. We performed ...