Debler, Lisa; Palmer, Annette; Braumüller, Sonja; Klohs, Bettina; Mollnes, Tom Eirik; Holzmann, Karlheinz; Huber-Lang, Markus; Halbgebauer, Rebecca (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-27)
The immune response following trauma represents a major driving force of organ dysfunction and poor outcome. Therefore, we investigated the influence of an additional hemorrhagic shock (HS) on the early posttraumatic immune dysbalance in the whole population of blood leukocytes. A well-established murine polytrauma (PT) model with or without an additional pressure-controlled HS (mean arterial pressure ...