Background - Cervical cancer is a preventable disease, despite being one of the most common types of female cancers worldwide. Integrating existing programs for cervical cancer screening with personalized risk prediction algorithms can improve population-level cancer prevention by enabling more targeted screening and contrive preventive healthcare innovations. While algorithms developed for cervical ...

The Svyatogor Ridge and surroundings, located on the sediment-covered western flank of the Northern Knipovich Ridge, host extensive gas hydrate and related fluid flow systems. The fluid flow system here manifests in the upper sedimentary sequence as gas hydrates and free gas, indicated by bottom simulating reflections (BSRs) and amplitude anomalies. Using 2D seismic lines and bathymetric data, we ...

<p>The cryosphere of Arctic regions is undergoing rapid change due to century-scale global warming superimposed on millennial-scale natural climatic perturbations that started at the end of the last glacial cycle approximately 20,000 years ago [Slaymaker and Kelly, 2009]. The cryosphere refers to areas where low temperatures freeze water and form ice in the ocean (sea ice), on land (glaciers, ...

Our current understanding of how low antibiotic concentrations shape the evolution of contemporary β-lactamases is limited. Using the widespread carbapenemase OXA-48, we tested the long-standing hypothesis that selective compartments with low antibiotic concentrations cause standing genetic diversity that could act as a gateway to developing clinical resistance. Here, we subjected <i>Escherichia ...

Elongate inclusions immersed in a viscous fluid generally rotate at a rate that is different from the local angular velocity of the flow. Often, a net alignment of the inclusions develops, and the resulting shape preferred orientation of the particle ensemble can then be used as a strain marker that allows reconstruction of the fluid’s velocity field. Much of the previous work on the dynamics of ...

The crystal structure of haemoglobin from Atlantic cod has been solved to 2.54 A˚ resolution. The structure consists of two tetramers in the crystallographic asymmetric unit. The structure of haemoglobin obtained from one individual cod suggests polymorphism in the tetrameric assembly.

L‐2,4‐diaminobutyric acid (DABA) aminotransferases can catalyze the formation of amines at the distal ω‐position of substrates, and is the intial and rate‐limiting enzyme in the biosynthesis pathway of the cytoprotecting molecule (S)‐2‐methyl‐1,4,5,6‐tetrahydro‐4‐pyrimidine carboxylic acid (ectoine). Although there is an industrial interest in the biosynthesis of ectoine, the DABA aminotransferases ...

Background: Individuals with intellectual disabilities (ID) often face barriers when trying to engage in physical activity. Exergames, which combine physical exercise with gaming technology, have shown the potential to promote physical activity among this group of individuals. However, the suitability of exergames for individuals with ID from different cultural backgrounds has received ...

Som et av verdens mest digitaliserte land forvalter norske virksomheter store deler av sine verdier gjennom det digitale domenet. Digitalisering er viktig for både vekst og verdiskapning, men sikkerhetsutfordringene er også store, og de senere års nasjonale trusselvurderinger har hatt et økende fokus på den digitale trusselen. Derfor er cybersikkerhet som begrep blitt mer fremtredende de siste årene. ...

The experimental UV and CV of five substituted 2-hydroxybenzophenones in solvents acetonitrile, n-dimethylformamide and dimethylsulfoxide are presented. Results obtained were used to determine their experimental highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO) and the results were compared to their theoretical model. The derivatives with an electron withdrawing ...