Jadhav, Pankaj; Sinha, Vikrant; Chugh, Saurabh; Kotyada, Chaithanya; Bachhav, Digvijay; Singh, Ramandeep; Rothweiler, Ulli; Singh, Mahavir (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-29)
The toxin–antitoxin (TA) systems are small operon systems that are involved in important physiological processes in bacteria such as stress response and persister cell formation. Escherichia coli HigBA complex belongs to the type II TA systems and consists of a protein toxin called HigB and a protein antitoxin called HigA. The toxin HigB is a ribosome-dependent endoribonuclease that cleaves the ...