Xanthines such as caffeine and theobromine are among the most consumed psychoactive stimulants in the world, either as natural components of cofee, tea and chocolate, or as added ingredients. The present study assessed if xanthines affect liver sinusoidal endothelial cells (LSEC). Cultured primary rat LSEC were challenged with xanthines at concentrations typically obtained from normal consumption of ...

The sea area around the Orkney archipelago, Scotland is subjected to substantial maritime shipping activities. By contract, the Svalbard archipelago, Norway currently has a rather low marine traffic profile. Future projections, however, indicate that the Trans-Arctic route might change the whole transportation picture and Svalbard may be at the centre of maritime activities. Both archipelagos ...

In this paper, we investigate overdetermined systems of scalar PDEs on the plane with one common characteristic, whose general solution depends on one function of one variable. We describe linearization of such systems and their integration via Laplace transformation, relating this to Lie's integration theorem and formal theory of PDEs.

<p>Nudge principles and techniques are significant in communications, marketing, and groups’ motivation to improve personal health, wealth, and well-being. We make numerous decisions in online situations. People’s health and well-being have garnered widespread interest and concern in this wearable’s age. Smart nudging is defined as “digital nudging, where the guidance of user behavior is tailored ...

A client-side approach brings great opportunities for flexible personalization of timed media experiences. This, turns it into a challenge of UX development. However, UX development does not support time-driven rendering or shared interactivity, which are required by media related scenarios. Moreover, UX development is already quite complicated, so adding support for timed rendering and shared ...

<p>The geologic history of the SW Eurasian Basin and the northern Svalbard/Barents Sea continental margin started in Late Cretaceous / early Tertiary. Since about 50 Ma seafloor spreading has been active in the Eurasian Basin splitting off the Lomonosov Ridge from the northern Eurasian Shelf. Since Miocene, rifting and seafloor spreading have been also established in between NE Greenland and Svalbard, ...

Should humans work? A simple question at a time when the advent of AI, automation and robotics claims a privileged position in the future of work. The question is perplexing and confusing however once we enquire into the meaning of technology and work as such: some claim that human jobs and well-being might be threatened by technological advances while others predict an increase in high skilled ...

Holocene relative shore-level changes and development of the G ipka palaeolagoon in the western Gulf of Riga are reconstructed using multiproxy analyses by combining litho-, biostratigraphical and chronological data with remote sensing and geophysical data. The results show the development of the G ipka basin from the Ancylus Lake/Initial Litorina Sea coastal zone (before c. 9.1 cal. ka BP) to ...

The geological evolution of the northern Barents Shelf is complex, and the area has undergone several phases of tectonic activity leading to a mosaic of several deep and shallow basins, platforms, salt-cored domes and structural highs. The area is highly gas prone with some very few commercial oil discoveries, and only two fields currently in production. Deep burial and subsequent Late Cretaceous–Cenozoic ...