miR-126 as a prognostic marker in non-GIST soft tissue sarcoma
Description and presentation of results of miRNA expression profiling (Exiqon) (PDF)
ForfatterPersson, Magnus Lennart
The aim of the study was to study the prognostic impact of miRNAs in non-GIST soft tissue sarcoma. The method used was microarray-based miRNA expression profiling of all verified human miRNAs on a selected number of samples. Selection criteria was time of survival (long and short). Then, the significance of miR-126 expression for disiease-specific survival in the total patient cohort of non-GIST STS was decided to be explored. miR-126 is known to be a key factor in tumor development for many carcinomas, but the role of miR-126 in sarcoma is less well described. That was the reason for selecting miR-126.
ForlagUiT Norges arktiske universitet
UiT The Arctic University of Norway
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