Browsing by Author "Evjenth, Bjørg"
-
Bradykinin-Induced Shock Increase Exhaled Nitric Oxide, Complement Activation and Cytokine Production in Pigs
Seip, Knut Fredrik; Evjenth, Bjørg; Hovland, Anders; Dybwik, Knut Gustav; Johansen, Harald Thidemann; Fure, Hilde; Mollnes, Tom Eirik; Nielsen, Erik Waage (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-03-04)Bradykinin is an important mediator in blood pressure regulation, ischemic precondition and capillary leakage, allergy, anaphylaxis, inflammation, and nociception, at least partly via the generation of nitric oxide (NO). Macrophages are particularly abundant in the porcine lung circulation. Upon bradykinin binding macrophages release cytokines and endothelial ... -
Establishing IMMULITE® 2000 cut-off values for serum allergen-specific immunoglobulin and exploring their relationship to exhaled nitric oxide
Evjenth, Bjørg; Hansen, Tonje Elisabeth; Brekke, Ole Lars; Holt, Jan (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-03-31)Aim: Paediatric cut-off values for serum allergen-specific IgE (sIgE) using the Siemens IMMULITE 2000 system to diagnose allergic rhinoconjunctivitis have not been established. We aimed to determine cut-off levels for sIgE for 10 common inhalant allergens and to study the relationship between sIgE, total IgE and fractional exhaled nitric oxide (FENO). <br>Methods: We enrolled 243 schoolchildren, ... -
Fractional exhaled nitric oxide and its relation to exercise, asthma and allergic rhinoconjunctivitis in a subarctic childhood population. A study of asthma and allergy among schoolchildren in Nordland County.
Evjenth, Bjørg (Doctoral thesis; Doktorgradsavhandling, 2014-11-07)Astma og allergisk øye- og nesekatarr (rhinokonjunktivitt, AR) er de vanligste kroniske sykdommene blant barn i den vestlige verden. I de siste tiårene har prevalensen (forekomsten) av sykdommene økt betydelig, men i enkelte Europeiske land rapporteres det om en utflating i prevalensen av astma. I klinisk praksis brukes laboratorietester til å understøtte diagnosene astma og AR. Analyser av biologiske ... -
Increasing prevalence of asthma, allergic rhinoconjunctivitis and eczema among schoolchildren: three surveys during the period 1985-2008
Hansen, Tonje Elisabeth; Evjenth, Bjørg; Holt, Jan (Journal article; Tidsskriftartikkel; Peer reviewed, 2012-09-20)<p><i>Aim - </i>The prevalence of asthma, allergic rhinoconjunctivitis (AR) and eczema among children has increased worldwide in the last four decades, but recent studies disagree as to whether the prevalence is continuing to rise or is levelling off or declining. The aim of this study was to assess time trends in a subarctic population. <p><i>Methods - </i>A cross-sectional, questionnaire-based ... -
Lower respiratory tract infections appear to be the most important risk factor for current asthma in subarctic schoolchildren.
Hansen, Tonje Elisabeth; Evjenth, Bjørg; Holt, jan (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-01)<p><i>Aim - </i>The aim of this study was to identify possible risk factors for current asthma revealed by two studies in Northern Norway in 1985 and 2008 and to evaluate these factors contributing to the increased prevalence of asthma over these 23 years. <p><i>Methods - </i>As part of the ‘Asthma and allergy study among schoolchildren in Nordland county’ we performed a case–control study (70.0% ... -
Validation of a questionnaire against clinical assessment in the diagnosis of asthma in school children
Hansen, Tonje Elisabeth; Evjenth, Bjørg; Holt, Jan (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-10-08)<p><i>Aim: </i>A questionnaire has been used repeatedly in cross-sectional studies to determine the prevalence of asthma, allergic rhinoconjunctivitis (AR) and eczema among schoolchildren in Nordland County, Norway. The current study was designed to validate the questionnaire against clinical assessment as the diagnostic gold standard and to investigate the extent of possible misclassification. ...