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Lower respiratory tract infections appear to be the most important risk factor for current asthma in subarctic schoolchildren.

Permanent lenke
https://hdl.handle.net/10037/15379
DOI
https://doi.org/10.1111/apa.14603
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article.pdf (551.7Kb)
Accepted manuscript version (PDF)
Dato
2018-10-01
Type
Journal article
Tidsskriftartikkel
Peer reviewed

Forfatter
Hansen, Tonje Elisabeth; Evjenth, Bjørg; Holt, jan
Sammendrag

Aim - The aim of this study was to identify possible risk factors for current asthma revealed by two studies in Northern Norway in 1985 and 2008 and to evaluate these factors contributing to the increased prevalence of asthma over these 23 years.

Methods - As part of the ‘Asthma and allergy study among schoolchildren in Nordland county’ we performed a case–control study (70.0% attendance) comparing 153 children with current asthma (cases) to their non‐asthmatic controls. The results from this 2008 study were compared to a similar case–control study (93.2% attendance) performed in 1985 based on 62 current asthmatics.

Results - In 1985, the most important risk factors for current asthma were repeated lower respiratory tract infections (LRTIs) with adjusted odds ratio (aOR) 52.11, together with urticaria ever and atopic disease in the family. In 2008, the most important risk factors were food allergy with aOR 7.06, LRTIs during the first three years of life with aOR 5.80 and hospitalisation caused by LRTIs.

Conclusion - In both studies, LRTI was the most important risk factor for current asthma. Whether or not LRTIs have contributed to the increased asthma prevalence in this population over 23 years remains unresolved.

Beskrivelse
This is the peer reviewed version of the following article: Hansen, T.E., Evjenth, B. & Holt, J. (2018). Lower respiratory tract infections appear to be the most important risk factor for current asthma in subarctic schoolchildren. Acta Paediatrica, 108(5), 911-919, which has been published in final form at https://doi.org/10.1111/apa.14603. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
Er en del av
Hansen, T.E. (2019). The prevalence and possible risk factors of asthma in a subarctic child population. A study of asthma and allergy among schoolchildren i Nordland county. (Doctoral thesis). https://hdl.handle.net/10037/15313
Forlag
Wiley
Sitering
Hansen, T.E., Evjenth, B. & Holt, J. (2018). Lower respiratory tract infections appear to be the most important risk factor for current asthma in subarctic schoolchildren. Acta Paediatrica, 108(5), 911-919. https://doi.org/10.1111/apa.14603
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