• A 4-year follow-up of patients with medication-overuse headache previously included in a randomized multicentre study. 

      Salvesen, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      The aim of this study was to evaluate the longterm outcome in 61 patients with medication-overuse headache (MOH) who 4 years previously had been included in a randomized open-label prospective multicentre study. Sixty patients still alive after 4 years were invited to a follow-up investigation. Fifty patients (83%) participated. Sixteen visited a neurologist, 22 were interviewed through telephone, ...
    • Acceptability, feasibility, and cost of telemedicine for nonacute headaches: A randomized study comparing video and traditional consultations 

      Müller, Kai Ivar; Alstadhaug, Karl Bjørnar; Bekkelund, Svein Ivar (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05-30)
      <b>Backgr ound:</b> The feasibility of telemedicine in diagnosing and treating nonacute headaches, such as primary headaches (migraine and tension-type) and medication-overuse headaches has not been previously investigated. By eliminating the need of travel to specialists, telemedicine may of fer significant time and money ...
    • Accuracy of physical examination for chronic lumbar radiculopathy 

      Iversen, Trond; Solberg, Tore; Romner, Bertil; Wilsgaard, Tom; Nygaard, Øystein Petter; Waterloo, Knut; Brox, Jens Ivar; Ingebrigtsen, Tor (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Clinical examination of patients with chronic lumbar radiculopathy aims to clarify whether there is nerve root impingement. The aims of this study were to investigate the association between findings at clinical examination and nerve root impingement, to evaluate the accuracy of clinical index tests in a specialised care setting, and to see whether imaging clarifies the cause of chronic ...
    • Activation of Coagulation and Fibrinolysis in Acute Respiratory Distress Syndrome: A Prospective Pilot Study 

      Ozolina, Agnese; Sarkele, Marina; Sabelnikovs, Olegs; Skesters, Andrejs; Jaunalksne, Inta; Serova, Jelena; Ievins, Talins; Bjertnæs, Lars J.; Vanags, Indulis (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-28)
      Introduction: Coagulation and fibrinolysis remain sparsely addressed with regards to acute respiratory distress syndrome (ARDS). We hypothesized that ARDS development might be associated with changes in plasma coagulation and fibrinolysis. Our aim was to investigate the relationships between ARDS diagnosis and plasma concentrations of tissue factor (TF), tissue plasminogen activator (t-PA), and ...
    • Activity-related pain in patients with chronic musculoskeletal disorders 

      Damsgård, Elin; Thrane, Gyrd; Anke, Audny; Fors, Terese; Røe, Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)
      Purpose. Activity related pain may be a barrier to rehabilitation in patients with chronic musculoskeletal disorders. This study investigated patients’ reports of increased pain during activity, and the association between such pain and psychological factors and pain variables. Method. Questionnaires from 232 adults with chronic musculoskeletal pain measured pain intensity, spread of pain and ...
    • Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock 

      Orrem, Hilde L.; Nilsson, Per H.; Pischke, Søren Erik; Grindheim, Guro; Garred, Peter; Seljeflot, Ingebjørg; Husebye, Trygve; Aukrust, Pål; Yndestad, Arne; Andersen, Geir Ø.; Barratt-Due, Andreas; Mollnes, Tom Eirik (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-02-09)
      Aims: Heart failure (HF) is an impending complication to myocardial infarction. We hypothesized that the degree of complement activation reflects severity of HF following acute myocardial infarction. <br> <br> Methods and results: The LEAF trial (LEvosimendan in Acute heart Failure following myocardial infarction) evaluating 61 patients developing HF within 48 h after percutaneous coronary ...
    • Acute infection as a trigger for incident venous thromboembolism: Results from a population- based case- crossover study 

      Grimnes, Gro; Isaksen, Trond; Tichelaar, Ynse Ieuwe Gerardus Vladimir; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-21)
      Background:<br> A bidirectional relation exists between acute infection and immobilization, and both are triggers for venous thromboembolism (VTE). To what extent the association between infection and VTE‐risk is explained by immobilization is unknown. <br>Aims:<br> To investigate the impact of hospitalization with acute infection on the VTE‐risk in patients with and without concomitant ...
    • The acute phase of experimental cardiogenic shock is counteracted by microcirculatory and mitochondrial adaptations 

      Stenberg, Thor Allan; Kildal, Anders Benjamin; Sanden, Espen; How, Ole-Jakob; Hagve, Martin; Ytrehus, Kirsti; Larsen, Terje; Myrmel, Truls (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • An Acylation-Finkelstein Approach to Radioiodination of Bioactives: The Role of Amide Group Anchimeric Assistance 

      Fjellaksel, Richard; Dugalic, Damir; Demissie, Taye Beyene; Riss, Patrick; Hjelstuen, Ole Kristian; Sundset, Rune; Hansen, Jørn H (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-02-28)
      Herein, we report a straightforward sequential acylation‐Finkelstein approach to achieve iodination of amine containing bioactives. The utility was demonstrated by successful radiolabelling with <sup>123</sup>I in high radiochemical yield. Moreover, microwave‐assisted Finkelstein reaction can be employed to enhance conversion and reaction rates to obtain the desired iodides. The method is of interest ...
    • Adherence and factors affecting satisfaction in long-term telerehabilitation for patients with chronic obstructive pulmonary disease: a mixed methods study 

      Hoaas, Hanne; Andreassen, Hege K; Lien, Linda Aarøen; Hjalmarsen, Audhild; Zanaboni, Paolo (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-02-25)
      Background: Telemedicine may increase accessibility to pulmonary rehabilitation in chronic obstructive pulmonary disease (COPD), thus enhancing long-term exercise maintenance. We aimed to explore COPD patients’ adherence and experiences in long-term telerehabilitation to understand factors affecting satisfaction and potential for service improvements. <p>Methods: A two-year pilot study with 10 ...
    • Adoption of routine telemedicine in Norway: The current picture 

      Zanaboni, Paolo; Knarvik, Undine; Wootton, Richard (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
    • Adoption of telemedicine : from pilot stage to routine delivery 

      Zanaboni, Paolo; Wootton, Richard (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Today there is much debate about why telemedicine has stalled. Teleradiology is the only widespread telemedicine application. Other telemedicine applications appear to be promising candidates for widespread use, but they remain in the early adoption stage. The objective of this debate paper is to achieve a better understanding of the adoption of telemedicine, to assist those trying to move applications ...
    • Adverse events in hospitalised cancer patients: a comparison to a general hospital population 

      Haukland, Ellinor Christin; von Plessen, Christian; Nieder, Carsten; Vonen, Barthold (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-05)
      <p><i>Background</i>: Patients with cancer are often treated by many healthcare providers, receive complex and potentially toxic treatments that can increase the risk for iatrogenic harm. The aim of this study is to investigate whether hospitalised cancer patients are at higher risk of adverse events (AEs) compared to a general hospital population.</p> <p><i>Material and methods</i>: A total of ...
    • Agreement on web-based diagnoses and severity of mental health problems in Norwegian child and adolescent mental health services 

      Brøndbo, Per Håkan; Mathiassen, Børge Idar; Martinussen, Monica; Heiervang, Einar; Eriksen, Mads; Kvernmo, Siv (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Objective: This study examined the agreement between diagnoses and severity ratings assigned by clinicians using a structured web-based interview within a child and adolescent mental health outpatient setting. Method: Information on 100 youths was obtained from multiple informants through a web-based Development and Well-Being Assessment (DAWBA). Based on this information, four experienced ...
    • Air ambulance flights in northern Norway 2002- 2008. Increased number of secondary fixed wing (FW) operations and more use of rotor wing (RW) transports 

      Norum, Jan; Elsbak, Trond M (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Air ambulance service in Norway has been upgraded during the last years. European regulations concerning pilots’ working time and new treatment guidelines/strategies have called for more resources. The objective was to describe and analyse the two supplementary air ambulance [fixed wing (FW) and rotor wing (RW)] alternatives’ activity during the study period (2002-2008). Furthermore we aimed to ...
    • Air ambulance nurses as expert supplement to local emergency services 

      Wisborg, Torben; Bjerkan, Bjørn (Journal article; Tidsskriftartikkel; Peer reviewed, 2013-12-25)
      Introduction: Flight nurses in the Norwegian National Air Ambulance Service are specialist nurse anesthetists or intensive care nursing specialists. For air ambulance bases far from hospitals, these nurses represent otherwise unavailable competencies. This study reports a 6-year experience with flight nurse participation in local emergencies beyond the transportation phase. <br>Methods: The ...
    • Air ambulance services in the Arctic 1999-2009 : a Norwegian study. 

      Norum, Jan; Elsbak, Trond M (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Air ambulance services in the Arctic have to deal with remote locations, long distances, rough weather conditions and seasonable darkness. Despite these challenges, the people living in the area expect a high quality of specialist health care. The objective of this study was to analyse the air ambulance operations performed in the Norwegian Arctic and study variations in diagnoses and flight patterns ...
    • Airway management by physician-staffed Helicopter Emergency Medical Services – a prospective, multicentre, observational study of 2,327 patients 

      Sunde, Geir Arne; Heltne, Jon-Kenneth; Lockey, David; Burns, Brian; Sandberg, Mårten; Fredriksen, Knut; Hufthammer, Karl Ove; Soti, Akos; Lyon, Richard; Jäntti, Helena; Kämäräinen, Antti; Reid, Bjørn Ole; Silfvast, Tom; Harm, Falko; Sollid, Stephen J. M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-07)
      <p>Background: Despite numerous studies on prehospital airway management, results are difficult to compare due to inconsistent or heterogeneous data. The objective of this study was to assess advanced airway management from international physician-staffed helicopter emergency medical services. <p>Methods: We collected airway data from 21 helicopter emergency medical services in Australia, England, ...
    • Alcohol consumption, blood alcohol concentration level and guideline compliance in hospital referred patients with minimal, mild and moderate head injuries 

      Efskind, Marianne; Heskestad, Ben Ottar; Ingebrigtsen, Tor; Romner, Bertil; RØNNING, PÅL ANDRE; Helseth, Eirik (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      In 2000 the Scandinavian Neurotrauma Committee published guidelines for safe and cost-effective management of minimal, mild and moderate head injured patients. The aims of this study were to investigate to what extent the head injury population is under the influence of alcohol, and to evaluate whether the physicians’ compliance to the guidelines is affected when patients are influenced by ...
    • Alginate microbeads are complement compatible, in contrast to polycation containing microcapsules, as revealed in a human whole blood model 

      Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Strand, Berit Løkensgard; Skjåk-Bræk, Gudmund; Lacík, Igor; Espevik, Terje; Mollnes, Tom Eirik (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Alginate microbeads and microcapsules are presently under evaluation for future cell-based therapy. Defining their inflammatory properties with regard to humans is therefore essential. A lepirudine-based human whole blood model was used as an inflammation predictor by measuring complement and leukocyte stimulation. Alginate microbeads were complement-compatible since they did not activate complement ...