Recent additions

  • Mortality and alcohol-related morbidity in patients with delirium tremens, alcohol withdrawal state or alcohol dependence in Norway: A register-based prospective cohort study 

    Bramness, Jørgen Gustav; Heiberg, Ina Heidi; Høye, Anne; Rossow, Ingeborg Margrete (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-19)
    Background and Aims: Little is known about long-term consequences of delirium tremens (DT). This study aimed to compare all-cause and cause-specific mortality and alcohol-related morbidity between patients with: (i) DT, (ii) alcohol withdrawal state (AWS) and (iii) alcohol dependence (AD). Design: A national longitudinal health registry study with linked data from the Norwegian Patient Registry ...
  • Cryoneurolysis for cervicogenic headache - A double blinded randomized controlled study 

    Kvarstein, Gunnvald; Högström, Henrik; Allen, Sara Maria; Rosland, Jan Henrik (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-13)
    Background and aims - Cervicogenic headache (CEH) is a debilitating condition and analgesics have limited effect. Percutaneous cryoneurolysis is thus still in use although the clinical evidence is lacking. We present a randomized, controlled study to assess the clinical efficacy of cryoneurolysis compared with a corticosteroid combined with a local anaesthetic. <p> <p>Methods - In a university-based ...
  • Pain tolerance after stroke: The Tromsø study 

    Melum, Tonje Anita; Årnes, Anders; Stigum, Hein; Stubhaug, Audun; Steingrímsdóttir, Ólöf Anna; Mathiesen, Ellisiv B.; Nielsen, Christopher Sivert (Journal article; Tidsskriftartikkel, 2023-05-11)
    Background: Stroke lesions might alter pain processing and modulation by affecting the widely distributed network of brain regions involved. We aimed to compare pain tolerance in stroke survivors and stroke-free persons in the general population, with and without chronic pain.<p> <p>Methods: We included all participants of the sixth and seventh wave of the population-based Tromsø Study who had ...
  • Penicillin for enhver pris? 

    Thaulow, Christian Magnus; Klingenberg, Claus (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-26)
    Barn i trassalderen og bitre penicillinblandinger fire ganger i døgnet er en vanskelig kombinasjon. Smalspektret antibiotika er gullstandarden, men må balanseres opp mot barnets ubehag og etterlevelse av behandlingen.
  • Survival after cancer-related venous thrombosis: the Scandinavian Thrombosis and Cancer Study 

    Crobach, Monique J.T.; Anijs, Rayna J.S.; Brækkan, Sigrid Kufaas; Severinsen, Marianne T.; Hammerstrøm, Jens; Skille, Hanne; Kristensen, Søren R.; Paulsen, Benedikte; Tjønneland, Anne; Versteeg, Henri H.; Overvad, Kim; Hansen, John Bjarne; Næss, Inger Anne; Cannegieter, Suzanne C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-28)
    Patients with cancer have an increased risk of developing venous thromboembolism (VTE), and this combination is reported to result in poorer survival compared with cancer alone. This study aimed to investigate the impact of VTE on the survival of patients with cancer in a general population. The Scandinavian Thrombosis and Cancer (STAC) cohort, a population-based cohort including 144 952 participants ...
  • Surgical Complications in Postchemotherapy Retroperitoneal Lymph Node Dissection for Nonseminoma Germ Cell Tumour: A Population-based Study from the Swedish Norwegian Testicular Cancer Group 

    Gerdtsson, Axel; Håkansson, Ulf; Törnblom, Magnus; Jancke, George; Negaard, Helene Francisca Stigter; Glimelius, Ingrid; Halvorsen, Dag; Karlsdottir, Åsa; Haugnes, Hege Sagstuen; Andreassen, Kristine Engen; Larsen, Signe Melsen; Holmberg, Göran; Wahlqvist, Rolf; Tandstad, Torgrim; Cohn-Cedermark, Gabriella; Ståhl, Olof; Kjellmann, Anders (Preprint; Manuskript, 2020-09-08)
    Background - Reports on perioperative complications after postchemotherapy retroperitoneal lymph node dissection (PC-RPLND) for nonseminoma germ cell tumour (NSGCT) are from experienced single centres, with a lack of population-based studies.<p> <p>Objective - To assess the complications of bilateral and unilateral PC-RPLND.<p> <p>Design, setting, and participants - A prospective, population-based, ...
  • Autophagy and endocytosis – interconnections and interdependencies 

    Birgisdottir, Åsa birna; Johansen, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-22)
    Autophagy and endocytosis are membrane-vesicle-based cellular pathways for degradation and recycling of intracellular and extracellular components, respectively. These pathways have a common endpoint at the lysosome, where their cargo is degraded. In addition, the two pathways intersect at different stages during vesicle formation, fusion and trafficking, and share parts of the molecular machinery. ...
  • Expression and function of Leukotriene B4 receptors in human articular chondrocytes 

    Hansen, Ann Kristin; Indrevik, Jill-Tove; Figenschau, Yngve Anton; Martinez, Inigo Zubiavrre; Sveinbjørnsson, Baldur (Conference object; Konferansebidrag, 2013)
    Leukotriene B4 (LTB4) is linked to osteoarthritis (OA) development however the expression of LTB4 receptors in cartilage cells and the physiological effects of LTB4 on cartilage tissue remain unknown. In this study we find that human articular chondrocytes express LTB4 receptors and that these receptors are functional, however, LTB4 does not seem to affect importantly some primary chondrocyte functions.
  • Days at home in the last three months of life: patterns-of-care analysis in patients with non-small cell lung cancer 

    Nieder, Carsten; Aanes, Siv Gyda; Haukland, Ellinor Christin (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-27)
    Introduction: To calculate the number of days patients with terminal nonsmall cell lung cancer (NSCLC) spent at home in the last 3 months of life, and to identify factors that predict a lower proportion of days at home.<p> <p>Material and methods: Retrospective study of 434 deceased patients with NSCLC. The number of days spent in a hospital or nursing home was identified from electronic ...
  • Risk of Intraepithelial Neoplasia Grade 3 or Worse (CIN3+) among Women Examined by a 5-Type HPV mRNA Test during 2003 and 2004, Followed through 2015 

    Rad, Amir; Sørbye, Sveinung; Tiwari, Sweta; Løchen, Maja-Lisa; Skjeldestad, Finn Egil (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-08)
    Background: The study’s purpose was to evaluate the performance of a five-type HPV mRNA test to predict cervical intraepithelial neoplasia grade 3 or worse (CIN3+) during up to 12 years of follow-up. Methods: Overall, 19,153 women were recruited by gynecologists and general practitioners in different parts of Norway between 2003 and 2004. The study population comprised 9582 women of these women, ...
  • Practice patterns in diagnostics, staging, and management strategies of gallbladder cancer among Nordic tertiary centers 

    Takala, Sini; Lassen, Kristoffer; Søreide, Kjetil; Sparrelid, Ernesto; Angelsen, Jon-Helge; Bringeland, Erling Audun; Eilard, Malin S.; Hemmingsson, Oskar; Isaksson, Bengt; Karjula, Heikki; Lammi, Jukka-Pekka; Larsen, Peter N.; Lavonius, Maija; Lindell, Gert; Mortensen, Frank V.; Mortensen, Kim Erlend; Nordin, Arno; Pless, Torsten; Sandström, Per; Sandvik, Oddvar Mathias; Vaalavuo, Yrjö; Villard, Christina; Sallinen, Ville (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-28)
    Background and objective: Gallbladder cancer (GBC) is a rare malignancy in the Nordic countries and no common Nordic treatment guidelines exist. This study aimed to characterize the current diagnostic and treatment strategies in the Nordic countries and disclose differences in these strategies. Methods: This was a survey study with a cross-sectional questionnaire of all 19 university hospitals ...
  • The Knowledge of Implementation Strategies: Impact of the Installed Base 

    Pedersen, Rune; Nordheim, Espen Solbakken; Lintvedt, Ove Kumetz Bomhoff; Fagerlund, Asbjørn Johansen; Severinsen, Gro-Hilde; Malm-Nicolaisen, Kristian (Journal article; Tidsskriftartikkel; Peer reviewed, 2023)
    This study uses three case studies to investigate how the installed base affects Electronic Health Records (EHR) implementation in European hospitals: i) transition from paper-based records to EHRs; ii) replacement of an existing EHR with a similar system; and iii) replacing existing EHR system with a radically different one. Using a meta-analysis approach, the study employs the theoretical framework ...
  • How we treat octogenarians with brain metastases 

    Nieder, Carsten; Andratschke, Nicolaus H.; Grosu, Anca L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-08)
    Biologically younger, fully independent octogenarians are able to tolerate most oncological treatments. Increasing frailty results in decreasing eligibility for certain treatments, e.g., chemotherapy and surgery. Most brain metastases are not an isolated problem, but part of widespread cancer dissemination, often in combination with compromised performance status. Multidisciplinary assessment ...
  • PRO: Do We Still Need Whole-Brain Irradiation for Brain Metastases? 

    Popp, Ilinca; Hartong, Nanna E.; Nieder, Carsten; Grosu, Anca-L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-15)
    (1) Background: In recent decades, the use of whole-brain radiation therapy (WBRT) in the treatment of brain metastases has significantly decreased, with clinicians fearing adverse neurocognitive events and data showing limited efficacy regarding local tumor control and overall survival. The present study thus aimed to reassess the role that WBRT holds in the treatment of brain metastases. (2) ...
  • Epidemiology and Antimicrobial Susceptibility of Invasive Bacterial Infections in Children—A Population-Based Study From Norway 

    Thaulow, Christian Magnus; Lindemann, Paul Christoffer; Klingenberg, Claus; Berild, Dag; Blix, Hege Salvesen; Myklebust, Tor Åge; Harthug, Stig (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05)
    Objective: To describe epidemiology and antimicrobial susceptibility testing (AST) data of bacteria causing invasive infections in Norwegian children (0–18 years).<p> <p>Methods: Population-based observational study using prospectively collected AST data from the Norwegian Surveillance System of Antimicrobial Resistance from 2013 to 2017. We included all clinically relevant bacterial isolates ...
  • Biliverdin Reductase B Is a Plasma Biomarker for Intraplaque Hemorrhage and a Predictor of Ischemic Stroke in Patients with Symptomatic Carotid Atherosclerosis 

    Chemaly, Melody; Marlevi, David; Iglesias, Maria Jesus; Lengquist, Mariette; Kronqvist, Malin; Bos, Daniel; van Dam-Nolen, Dianne H. K.; van der Kolk, Anja; Hendrikse, Jeroen; Kassem, Mohamed; Matic, Ljubica; Odeberg, Jacob; de Vries, Margreet R.; Kooi, M. Eline; Hedin, Ulf (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-24)
    Background: Intraplaque hemorrhage (IPH) is a hallmark of atherosclerotic plaque instability. Biliverdin reductase B (BLVRB) is enriched in plasma and plaques from patients with symptomatic carotid atherosclerosis and functionally associated with IPH. Objective: We explored the biomarker potential of plasma BLVRB through (1) its correlation with IPH in carotid plaques assessed by magnetic resonance ...
  • Prospects of returning to work after lumbar spine surgery for patients considering disability pension: A nationwide study based on data from the Norwegian Registry for Spine Surgery 

    Hammer, Lovise; Ingebrigtsen, Tor; Gulati, Sasha; Hara, Sozaburo; Nygaard, Øystein Petter; Hara, Karen Walseth; Solberg, Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-09)
    Objectives To assess the odds for not returning to work (non-RTW) 1 year after treatment among patients who had applied for or were planning to apply for disability pension (DP-applicant) prior to an operation for degenerative disorders of the lumbar spine.<p> <p>Methods This population-based cohort study from the Norwegian Registry for Spine surgery included 26 688 cases operated for ...
  • S100A8 gene copy number and protein expression in breast cancer: associations with proliferation, histopathological grade and molecular subtypes 

    Børkja, Mathieu; Giambelluca, Miriam Soledad; Ytterhus, Borgny; Prestvik, Wenche Slettahjell; Bjørkøy, Geir; Bofin, Anna M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-14)
    Background and aims Amplification of S100A8 occurs in 10–30% of all breast cancers and has been linked to poorer prognosis. Similarly, the protein S100A8 is overexpressed in a roughly comparable proportion of breast cancers and is also found in infiltrating myeloid-lineage cells, again linked to poorer prognosis. We explore the relationship between these findings.<p> <p>Methods We examined S100A8 ...
  • Is the presence of foraminal stenosis associated with outcome in lumbar spinal stenosis patients treated with posterior microsurgical decompression 

    Aaen, Jørn Ståle; BANITALEBI, HASAN; Austevoll, Ivar Magne; Hellum, Christian; Storheim, Kjersti; Myklebust, Tor Åge; Anvar, Masoud D; Weber, Clemens; Solberg, Tore; Grundnes, Oliver; Brisby, Helena; Indrekvam, Kari; Hermansen, Erland (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-05)
    Background We aim to investigate associations between preoperative radiological findings of lumbar foraminal stenosis with clinical outcomes after posterior microsurgical decompression in patients with predominantly central lumbar spinal stenosis (LSS).<p> <p>Methods The study was an additional analysis in the NORDSTEN Spinal Stenosis Trial. In total, 230 men and 207 women (mean age 66.8 (SD ...
  • The Norwegian degenerative spondylolisthesis and spinal stenosis (NORDSTEN) study: study overview, organization structure and study population 

    Indrekvam, Kari; Bånerud, Ingrid Fjeldheim; Hermansen, Erland; Austevoll, Ivar Magne; Rekeland, Frode Gurvin; Guddal, Maren Hjelle; Solberg, Tore; Brox, Jens Ivar; Hellum, Christian; Storheim, Kjersti (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-03)
    Purpose To provide an overview of the The Norwegian Degenerative spondylolisthesis and spinal stenosis (NORDSTEN)- study and the organizational structure, and to evaluate the study population.<p> <p>Methods The NORDSTEN is a multicentre study with 10 year follow-up, conducted at 18 public hospitals. NORDSTEN includes three studies: (1) The randomized spinal stenosis trial comparing the impact of ...

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