Health conditions characterized by symptoms associated with chemical, physical and biological environmental factors unrelated to objectifiable pathophysiological mechanisms are often labelled by the general term “idiopathic environmental intolerances”. More specific, exposure-related terms are also used, e.g. “multiple chemical sensitivities”, “electromagnetic hypersensitivity” and “candidiasis ...

An integrated photonic chip based nanoscopy system has previously been developed at UiT, which allows for several advantages over conventional total internal reflection fluorescence microscopy and nanoscopy (i.e. super-resolutionnanoscopy). While the proof-of-concept has been demonstrated, there were several important system optimization tasks that were needed for making the ...

Alzheimer’s disease is the most common type of dementia; causing problems with memory, thinking and behaviour. The seemingly protective effect of hormone replacement therapy against Alzheimer’s disease sparked an interest in the role of the sex hormone system. Sex steroid production is dependent on gonadotropins released in the pituitary. The gonadotropin level is controlled by gonadotropin releasing ...

I Norge utgjør ikke-smittsomme sykdommer hele 87 % av sykdomsbyrden (FHI, 2018). Hovedårsaken til disse sykdommene er feilernæring (Mozaffarian, 2016). At fisk og sjømat er bra for helsen er godt akseptert, men helsefordelene har i hovedsak vært knyttet til den gunstige fettsyresammensetningen i sjømat. I de senere år har interessen for bioaktive komponenter økt, og marint restråstoff kan være en ...

Administering drug formulations to the vagina is a challenge since the vagina possesses “self-cleaning” features which allow trapping and rapid removing of foreign particles. Therefore, the residence time of drugs is often too short to offer a sufficient clinical effect. The aim of this project was to develop and optimize a liposomes-in-hydrogel system containing resveratrol for the local treatment ...

<i>Background</i> - Trauma-induced coagulopathy in patients with traumatic brain injury (TBI) is associated with high rates of complications, unfavourable outcomes and mortality. The mechanism of the development of TBI-associated coagulopathy is poorly understood.<br><br> <i>Methods</i> - This analysis, embedded in the prospective, multi-centred, observational Collaborative European NeuroTrauma ...

Lake‐dwelling fish that form species pairs/flocks characterized by body size divergence are important model systems for speciation research. Although several sources of divergent selection have been identified in these systems, their importance for driving the speciation process remains elusive. A major problem is that in retrospect, we cannot distinguish selection pressures that initiated divergence ...

This paper presents results from ongoing research with a goal to use a combination of time series from non-intrusive ambient sensors and deep recurrent neural networks to predict room usage at a university campus. Training data was created by collecting measurements from ambient sensors measuring room CO2, humidity, temperature, light, motion and sound, while the ground-truth counts was created ...

<p>Background: Interleukin 6 concentration is associated with myocardial injury, heart failure, and mortality after myocardial infarction. In the Norwegian tocilizumab non-ST-segment-elevation myocardial infarction trial, the first randomized trial of interleukin 6 blockade in myocardial infarction, concentration of both C-reactive protein and troponin T were reduced in the active treatment arm. In ...

The present thesis aims at using insights from ESM studies (i.e., frequent ecologically valid self-reports for approximately one week) to improve the treatment and the prediction psychotic symptoms. ESM indicates that warning signs, such as negative affect, worrying, sleep problems, or aberrant salience precede rapidly fluctuating psychotic symptoms throughout the day. Assuming underlying causal ...