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Physiotherapiewissenschaft umfassend verstehen: Ein angewandter Überblick über verschiedene Forschungsparadigmen (Teil 1)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-12-13)International health and physiotherapy research has developed over the last few decades through the use and further development of a wide range of scientific theories. This enables researchers to address current issues more appropriately and contribute to change. In German-speaking countries, this diversity of scientific grounding has yet to be developed. The common distinction between quantitative ... -
Physiotherapiewissenschaft umfassend verstehen: Ein angewandter Überblick über verschiedene Forschungsparadigmen (Teil 2)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-12-13)International health and physiotherapy research has developed over the last few decades through the use and further development of a wide range of scientific theories. This enables researchers to address current issues more appropriately and contribute to change. In German-speaking countries, this diversity of scientific grounding has yet to be developed. The common distinction between quantitative ... -
Targeting virulence: Activity-Based Protein Profiling (ABPP) for Discovery of Potential Therapeutic Targets in Enterococcus faecium
(Doctoral thesis; Doktorgradsavhandling, 2025-03-14)<i>Enterococcus faecium</i>, a gut commensal bacterium, has become a significant nosocomial and opportunistic pathogen, linked to infections like urinary tract infections, bacteraemia, and endocarditis. Its success as a pathogen is partly due to its high level of resistance to antibacterial agents. These resistance mechanisms are complicating treatment, especially in strains resistant to vancomycin, ... -
Geografiske Forskjeller i Behandling og Prognose ved Akutt Hjerneinfarkt i Troms Fylke
(Master thesis; Mastergradsoppgave, 2021-05-31)Hjerneslag rammer om lag 12 000 mennesker i Norge hvert år, og er en av de hyppigste dødsårsakene globalt. Prognosen korrelerer sterkt med tid fra symptomdebut til behandling. Trombolysebehandling bør gis så fort som mulig innen 4,5 timer. I Nord-Norge er det store avstander, og det kan være lang transporttid fra distrikt til sykehus. Målet med denne oppgaven er å se om det er like muligheter for ... -
Policy documents considering biodiversity, land use, and climate in the European Arctic reveal visible, hidden, and imagined nexus approaches
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-03)The Arctic is experiencing rapid and interlinked socio-environmental changes. Therefore, governance approaches that take the complex interactions between climate change, biodiversity loss, increasing land use pressures, and local livelihoods into account are needed: nexus approaches. However, an overview of whether and to what extent Arctic policies address these nexus elements in concert has ... -
Lifestyle changes in middle age and risk of cancer: evidence from the European Prospective Investigation into Cancer and Nutrition
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-05)In this study, we aimed to provide novel evidence on the impact of changing lifestyle habits on cancer risk. In the EPIC cohort, 295,865 middle-aged participants returned a lifestyle questionnaire at baseline and during follow-up. At both timepoints, we calculated a healthy lifestyle index (HLI) score based on cigarette smoking, alcohol consumption, body mass index and physical activity. HLI ranged ... -
Transcriptional responses to Piscine orthoreovirus (PRV) and stress hormones in Atlantic salmon (Salmo salar) red blood cells
(Doctoral thesis; Doktorgradsavhandling, 2025-03-14)Fish red blood cells (RBCs) are nucleated and metabolically active with physiological and immunological properties. Salmonid RBCs are target cells of Piscine orthoreovirus (PRV), a double-stranded RNA virus with three known genotypes (PRV-1, 2 and 3). PRV-1 can give heart and skeletal muscle inflammation to farmed Atlantic salmon, which can lead to mortality in combination with stress, PRV-3 is ... -
Perspectives from science teacher educators on the potential contribution of Sámi traditional knowledge to sustainable development
(Journal article; Tidsskriftartikkel; Peer reviewed, 2025-02-25)Introduction: This study investigates how Sámi traditional knowledge is integrated in science teacher education in Norway, and what teacher educators declare about its potential contribution to sustainable development.<p> <p>Methods: Data was collected through an anonymous electronic survey and analyzed by means of both qualitative and quantitative methods. Thirty-nine respondents from 15 teacher ... -
The Evolvement of Session Design From Junior Age to Senior Peak Performance in World-Class Cross-Country Skiers
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-08-21)Purpose: To compare designs of training sessions applied by world-class cross-country skiers during their most successful junior and senior season. <p> <p>Methods: Retrospective analysis of self-reported training characteristics (ie, training form, intensity, and exercise mode) among 8 male and 7 female world-class cross-country skiers was conducted. <p> <p>Results: Total number of sessions ... -
Long-range correlations with finite-size effects from a superposition of uncorrelated pulses with power-law distributed durations
(Journal article; Tidsskriftartikkel; Peer reviewed, 2025-02-26)Long-range correlations manifested as power spectral density scaling 1/<i>f<sup>β</sup></i> for frequency f and a range of exponents <i>β</i> are investigated for a superposition of uncorrelated pulses with distributed durations τ. Closed-form expressions for the frequency power spectral density are derived for a one-sided exponential pulse function and several variants of bounded and unbounded ... -
Association of Psychological Problems for Which Help Was Sought With Physical Illness
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-12-10)Introduction - Persons with mental disorders are at increased risk for physical illness. Individuals who seek help for psychological problems might benefit from timely support and interventional approaches. This study aimed to explore the associations between psychological problems for which help was sought and physical illness.<p> <p>Methods - The 7th survey of the Tromsø Study, which included ... -
Comprehensive security, disinformation, and COVID-19: An analysis of the impacts of mis- and disinformation and populist narratives during the pandemic
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-23)The COVID-19 pandemic has generated many fundamental and challenging implications regarding security, for both states and people. This article addresses the pandemic as a security threat, whereby societal and human dimensions of security are intertwined with the narrower (so-called traditional) state dimensions, culminating in comprehensive security. This article uses mixed methods, combining desk ... -
Pain prevalence rates and the mediating role of negative affect in adults referred to personality disorder treatment: A cross-sectional study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-10-29)Personality disorders (PDs) are prevalent among individuals with chronic pain, but less is known about the prevalence of pain in the PD population. This study therefore sought to explore the prevalence of current or everyday pain among individuals referred to outpatient PD treatment, and further explore the mediating role of negative affect in the relationship between PD severity and current pain. ... -
NLRP3 inflammasome mediates astroglial dysregulation of innate and adaptive immune responses in schizophrenia
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-11-30)Mounting evidence indicates the involvement of neuroinflammation in the development of schizophrenia (SCZ), but the potential role of astroglia in this phenomenon remains poorly understood. We assessed the molecular and functional consequences of inflammasome activation using induced pluripotent stem cell (iPSC)-derived astrocytes generated from SCZ patients and healthy controls (CTRL). Screening ... -
A descriptive and interpretive theory of ethical responsibility in public health nursing
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-10-15)This article presents a descriptive, interpretive theory of ethical responsibility in public health nursing. The theory is based on qualitative empirical studies, a purposeful literature review and meta-ethnography of public health nurses’ experiences of ethical responsibility, interpreted within a philosophical framework. Levianasian philosophy provides the main direction for the authors’ ... -
Spesialistutdanning av kardiologer i Norge - en spørreundersøkelse
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024)Spesialisering innen hjertesykdommer har over lengre tid vært populært og rekrutteringssterkt, men det er ingen oversikt over hvor mange leger i spesialisering (LIS) i hjertesykdommer som jobber ved norske sykehus. Det er også til en viss grad uvisst hvordan LIS i hjertesykdommer opplever spesialiseringsløpet, arbeidsforholdene og arbeidsmiljø. I et forsøk på å kartlegge disse forholdene sendte ... -
β-adrenergic stimulation after rewarming does not mitigate hypothermia-induced contractile dysfunction in rat cardiomyocytes
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-06-25)Victims of severe accidental hypothermia are frequently treated with catecholamines to counteract the hemodynamic instability associated with hypothermia-induced cardiac contractile dysfunction. However, we previously reported that the inotropic effects of epinephrine are diminished after hypothermia and rewarming (H/R) in an intact animal model. Thus, the goal of this study was to investigate the ... -
Effect of chemotherapeutic agents on natural transformation frequency in Acinetobacter baylyi
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-07-10)Natural transformation is the ability of a bacterial cell to take up extracellular DNA which is subsequently available for recombination into the chromosome (or maintenance as an extrachromosomal element). Like other mechanisms of horizontal gene transfer, natural transformation is a significant driver for the dissemination of antimicrobial resistance. Recent studies have shown that many pharmaceutical ... -
Psoriasis and vitamin D: Insights from a randomised clinical trial, a cross-sectional analysis of the Tromsø Study 2015-16 and a factorial Mendelian randomisation study using the UK Biobank and HUNT
(Doctoral thesis; Doktorgradsavhandling, 2025-03-14)Association between the skin disease psoriasis and lower serum 25-hydroxyvitamin D (25[OH]D) levels has been found in some studies. Overweight is considered a risk factor for both psoriasis and vitamin D deficiency. Topical vitamin D analogues are routine treatment for psoriasis, but effect of per oral supplementation is not established. This thesis aimed to enhance understanding of the link between ... -
New xenophyophores (Foraminifera, Monothalamea) from the eastern Clarion-Clipperton Zone (equatorial Pacific)
(Journal article; Tidsskriftartikkel, 2024-03-06)Xenophyophores are large, agglutinated foraminifera that dominate the benthic megafauna in some parts of the deep sea. Here, we describe an assemblage of largely fragmentary specimens from the Clarion-Clipperton Zone (CCZ), an area of the eastern abyssal Pacific hosting large, commercially significant deposits of polymetallic nodules. We recognised 18 morphospecies of which eight yielded DNA sequences. ...