<i>Objective</i> - Sarcopenia has been defined as age-related loss of muscle mass and function. The aim of this randomized controlled trial was to examine the effects of a 10-week instructor-led resistance training program on functional strength and body composition in men and women aged 70 years with pre-sarcopenia.<p> <p><i>Design, Setting, and Participants</i> - Participants were randomized ...

<i>Background</i> - There is increasing evidence that folate, an important component of one-carbon metabolism, modulates the epigenome. Alcohol, which can disrupt folate absorption, is also known to affect the epigenome. We investigated the association of dietary folate and alcohol intake on leukocyte DNA methylation levels in the European Prospective Investigation into Cancer and Nutrition (EPIC) ...

We construct high-order derivative operators for smooth functions represented via discontinuous multiwavelet bases. The need for such operators arises in order to avoid artifacts when computing functionals involving high-order derivatives of solutions of integral equations. Previously high-order derivatives had to be formed by repeated application of a first-derivative operator that, while uniquely ...

<i>Introduction</i> - Surveillance of unintended effects of pharmaceuticals (pharmacovigilance or drug safety) is crucial, as knowledge of rare or late side effects is limited at the time of the introduction of new medications into the market. Side effects of drugs may involve increased or decreased risk of cancer, but these typically appear after a long induction period. This fact, together with ...

<ol> <li>Assessing the effectiveness of conservation actions to halt population declines is challenging when confounded by other factors. We assessed whether culling of red fox, a predator currently increasing in number in the sub‐Arctic, contributed to recent recovery of the critically endangered Fennoscandian population of Lesser White‐fronted Goose <i>Anser erythropus</i>, while controlling for ...

The complement and coagulation systems are two interrelated plasma protein cascades. Evidence from observational and animal studies has proposed a role for the complement system in the development of venous thromboembolism (VTE), but the exact mechanisms remain obscure. The aim of this thesis was to investigate whether activation of the complement system impacts the risk of VTE and to investigate ...

The monitoring of Chlorophyll-a (Chl-a) concentration in high northern latitude waters has been receiving increased focus due to the rapid environmental changes in the sub-Arctic, Arctic. Spaceborne optical instruments allow the continuous monitoring of the occurrence, distribution, and amount of Chl-a. In recent years, the Ocean and Land Color Instruments (OLCI) onboard the Sentinel 3 (S3) A and B ...

Synthetic aperture radar data acquired by the Radar Imaging Satellite (RISAT-1) over experimental oil spills is here investigated. One quad-polarization scene in the Fine Resolution Alternate Polarization Stripmap (FRS-2) mode is analyzed to evaluate the potential of using this mode for oil spill observation.<br> Oil slicks of varying type and age are clearly detected in the HH and VV channels, with ...

A new Jensen inequality for multivariate superquadratic functions is derived and proved. The derived Jensen inequality is then employed to obtain the general Hardy-type integral inequality for superquadratic and subquadratic functions of several variables.

More and more underground spaces were used in 21st century because of rapid urbanization, traffic problems, etc. Underground city, metro, tunnel, mine, industrial and agriculture engineering, civil air defence engineering need large underground spaces. Underground spaces with different thermal, ventilation and lighting environments may cause comfort, health and safety problems. Concrete problems ...