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Accuracy and agreement of national spine register data for 474 patients compared to corresponding electronic patient records
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-06)Purpose - Data quality is essential for all types of research, including health registers. However, data quality is rarely reported. We aimed to assess the accuracy of data in a national spine register (NORspine) and its agreement with corresponding data in electronic patient records (EPR).<p> <p>Methods - We compared data in NORspine registry against data in (EPR) for 474 patients operated for ... -
Geographical variation in ADHD: do diagnoses refect symptom levels?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-18)Rates of ADHD diagnosis vary across regions in many countries. However, no prior study has investigated how much within-country geographic variation in ADHD diagnoses is explained by variation in ADHD symptom levels. We examine whether ADHD symptom levels explain variation in ADHD diagnoses among children and adolescents using nationwide survey and register data in Norway. Geographical variation in ... -
Explaining risk reductions in medical practice : prevention or postponement?
(Doctoral thesis; Doktorgradsavhandling, 2008)Diagnosis, treatment and follow up of risk conditions such as hypercholesterolemia and osteoporosis are prominent tasks of contemporary medical practice. The aim is to prevent, or at least postpone the onset of adverse health outcomes such as angina pectoris, heart attacks, strokes and fractures. Dealing with risks involves decision making under uncertainty. For patients to be able to engage ... -
A comprehensive statistical analysis for residuals of wind speed and direction from numerical weather prediction for wind energy
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-30)Wind data are vital for the research in renewable energy research. Their quality from numerical weather prediction significantly influences the wind energy models. This paper utilizes a comprehensive statistical analysis for analyzing predictive errors, named residuals of wind speed and direction modeled by numerical weather prediction models. The analysis, taken an Arctic wind site as an example, ... -
High abundances of small copepods early developmental stages and nauplii strengthen the perception of a non-dormant Arctic winter
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-15)The traditional view is that the Arctic polar night is a quiescent period for marine life, but recent reports of high levels of feeding and reproduction in both pelagic and benthic taxa have challenged this. We examined the zooplankton community present in Svalbard fjords, coastal waters, and the shelf break north of Svalbard, during the polar night. We focused on the population structure of abundant ... -
Experimental evidence of antimicrobial activity in Antarctic seaweeds: ecological role and antibiotic potential
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-25)Seaweeds contain a wide range of secondary metabolites which serve multiple functions, including chemical and ecological mediation with microorganisms. Moreover, owing to their diverse bioactivity, including their antibiotic properties, they show potential for human use. Nonetheless, the chemical ecology of seaweeds is not equally understood across different regions; for example, Antarctic seaweeds ... -
Screen-detected and interval breast cancer after concordant and discordant interpretations in a population based screening program using independent double reading
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-02)Objectives - To analyze rates, odds ratios (OR), and characteristics of screen-detected and interval cancers after concordant and discordant initial interpretations and consensus in a population-based screening program.<p> <p>Methods - Data were extracted from the Cancer Registry of Norway for 487,118 women who participated in BreastScreen Norway, 2006–2017, with 2 years of follow-up. All mammograms ... -
Social identity and risky leisure activities: implications for welfare and policy
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-22)In this paper, we build on theories in psychology and economics and link positional preferences to private agents’ identification with a social group, and the social norms present in that group. The purpose of our paper is to analyze behavioral, welfare, and policy implications of a link between private agents´ social identity and a risky leisure activity. Our results suggest that, when the outcome ... -
Trends in Hip Fracture Incidence, Length of Hospital Stay, and 30-Day Mortality in Sweden from 1998–2017: A Nationwide Cohort Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-15)In this nationwide cohort study, we investigated trends in hip fracture incidence, hospital length of stay (LOS), and 30-day mortality after admission in Sweden. The cohort included all individuals in Sweden aged ≥ 50 years with a first hip fracture diagnosis during 1998–2017 (N = 313,761). The outcomes were hip fracture incidence and 30-day mortality. The results showed that the incidence of hip ... -
Medication adherence among persons with coronary heart disease and associations with blood pressure and low-density-lipoprotein-cholesterol
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-21)Purpose - To describe medication adherence to lipid-lowering drugs (LLDs), antihypertensive drugs, and acetylsalicylic acid (ASA) among persons with coronary heart disease (CHD) and explore its association with low-density-lipoprotein (LDL)-cholesterol, and systolic and diastolic blood pressure.<p> <p>Methods - Based on record linkage between the seventh wave of the Tromsø Study and the Norwegian ... -
Automated segmentation of magnetic resonance bone marrow signal: a feasibility study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-02)Background - Manual assessment of bone marrow signal is time-consuming and requires meticulous standardisation to secure adequate precision of findings.<p> <p>Objective - We examined the feasibility of using deep learning for automated segmentation of bone marrow signal in children and adolescents.<p> <p>Materials and methods - We selected knee images from 95 whole-body MRI examinations of ... -
Whole-body MRI in children aged 6–18 years. Reliability of identifying and grading high signal intensity changes within bone marrow
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-21)Background - Whole-body magnetic resonance imaging (MRI) is increasingly being used in children, however, to date there are no studies addressing the reliability of the findings.<p> <p>Objective - To examine intra- and interobserver reliability of a scoring system for assessment of high signal areas within the bone marrow, as visualized on T2-weighted, fat-saturated images.<p> <p>Materials and ... -
New distribution records of kelp in the Kitikmeot Region, Northwest Passage, Canada, fill a pan-Arctic gap
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-01)Kelps play important roles in ecosystems as they provide structural habitat and protection, and supply food. Given these beneficial roles and observed increases in seaweed biomass and distribution ranges across the Arctic, mapping kelp occurrence around Arctic coasts is both timely and necessary for future conservation. Here, we fill spatial gaps in the knowledge of kelp distribution in the southern ... -
Multidisciplinary biophotonics, open science, and. . . plug & pray deep learning?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-06)Due to its great creative potential for innovation and scientific discovery, inter- and multidisciplinary collaboration is being increasingly encouraged by institutions and funding agencies. The increased opportunities in the multidisciplinary arena also come with significant challenges like the added experimental, analytical and logistical complexity, blended with a high likelihood of miscommunications. ... -
Protocol for Isolation and Culture of Mouse Hepatocytes (HCs), Kupffer Cells (KCs), and Liver Sinusoidal Endothelial Cells (LSECs) in Analyses of Hepatic Drug Distribution
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-25)Development of the new generation of drugs (e.g., oligo- and polynucleotides administered intravascularly either as free compounds or as nano-formulations) frequently encounters major challenges such as lack of control of targeting and/or delivery. Uncontrolled or unwanted clearance by the liver is a well-known and particularly important hurdle in this respect. Hence, reliable techniques are needed ... -
Symmetries of supergeometries related to nonholonomic superdistributions
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-06)We extend Tanaka theory to the context of supergeometry and obtain an upper bound on the supersymmetry dimension of geometric structures related to strongly regular bracket-generating distributions on supermanifolds and their structure reductions. -
Weighted Boundedness of Certain Sublinear Operators in Generalized Morrey Spaces on Quasi-Metric Measure Spaces Under the Growth Condition
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-17)We prove weighted boundedness of Calderón–Zygmund and maximal singular operators in generalized Morrey spaces on quasi-metric measure spaces, in general non-homogeneous, only under the growth condition on the measure, for a certain class of weights. Weights and characteristic of the spaces are independent of each other. Weighted boundedness of the maximal operator is also proved in the case when ... -
Statistical supervised learning with engineering data: a case study of low frequency noise measured on semiconductor devices
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-04)Our practical motivation is the analysis of potential correlations between spectral noise current and threshold voltage from common on-wafer MOSFETs. The usual strategy leads to the use of standard techniques based on Normal linear regression easily accessible in all statistical software (both free or commercial). However, these statistical methods are not appropriate because the assumptions they ... -
Iron status and prevalence of hereditary haemochromatosis in a multiethnic population in northern Norway : the SAMINOR study, the Sør-Varanger study, the Tromsø V study
(Doctoral thesis; Doktorgradsavhandling, 2008)Iron status is influenced by several factors such as nutritional factors and blood loss. Tron deficiency is one of the most severe and important nutritional deficiencies in the world today, both in industrialised as well as developing countries [1-3]. In normal subjects the total daily loss of iron is balanced by an equivalent amount of iron absorbed from the diet. When this equilibrium is ... -
Five years of exercise intervention at different intensities and development of white matter hyperintensities in community dwelling older adults, a Generation 100 sub-study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-18)We investigated if a five-year supervised exercise intervention with moderate-intensity continuous training (MICT) or high-intensity interval training (HIIT) versus control; physical activity according to national guidelines, attenuated the growth of white matter hyperintensities (WMH). We hypothesized that supervised exercise, in particular HIIT, reduced WMH growth. Older adults from the general ...