Browsing Doktorgradsavhandlinger (Helsefak) by Title
Now showing items 192-211 of 697
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e-Rehabilitation: Design and Effectiveness of a Tailored Internet- and Mobile-based Intervention to Support Maintenance of Physical Activity after Cardiac Rehabilitation
(Doctoral thesis; Doktorgradsavhandling, 2014-05-05)Hovedmålet i prosjektet var å tilby en effektiv Internet- og mobiltelefonbasert støtte til opprettholdelse av fysisk aktivitet hos hjerte-kar pasienter etter et rehabiliteringsopphold. For å få laget et godt støtteprogram som både var var effektivt i forhold til å støtte livsstilsending og meningsfullt å bruke ble innspill fra brukerne kombinert med et sterkt teoretisk rammeverk (modeller for ... -
Early markers of metabolic disease in obesity - A study of postprandial triglycerides, leptin and adiponectin interactions in the view of normal and dysregulated metabolism
(Doctoral thesis; Doktorgradsavhandling, 2019-12-06)Individuals in industrialized countries spend a substantial part of life in the non-fasting, postprandial state, which is also associated with increased oxidation and inflammation. Furthermore, a high body mass index (BMI) is the third cause of mortality in the world. In this PhD thesis, obese (BMI>30) individuals with and without metabolic disease (n=50) was included, in addition to a normal ... -
Early Markers of Metabolic Dysregulation in Obese Individuals - Identification at Baseline and Effect of Modest Weight Loss
(Doctoral thesis; Doktorgradsavhandling, 2023-11-15)<p><i>Background:</i> Evidence suggests that the link between obesity and chronic lifestyle disease is chronic, low-grade inflammation. Leptin and adiponectin play principal roles in inducing inflammation and promoting insulin resistance, resulting in metabolic syndrome. Our study aimed to find clinically feasible biologic markers to identify metabolically dysregulated obese individuals and to study ... -
Eclampsia, maternal deaths, and hypertensive diseases of pregnancy and long term maternal health risk
(Doctoral thesis; Doktorgradsavhandling, 2011-11-10)Det er viktig å kartlegge og gjennomgå alvorlige hendelser i forbindelse med svangerskap og fødsel. I dette arbeidet er det satt fokus på to dramatiske komplikasjoner; kvinner som har svangerskapsforgiftning (preeklampsi) og får kramer (eklampsi) og kvinner som dør i forbindelse med svangerskap og fødsel. I samarbeid med kolleger i Norge, Danmark og Sverige gjennomførte vi en registrering av ... -
Ecotoxicological assessment of Roundup-ready soybean agriculture investigated in a D. magna model
(Doctoral thesis; Doktorgradsavhandling, 2015-06-09)Transgenic glyphosate tolerant soybeans are constituents of an industrial production system with specific agricultural practices and supplementary agrochemicals as interwoven additional elements. Thus the material produced should not be seen as an isolated product of a specific modified genotype but rather as a product of a tailored agriculture system. This globally dominant crop has been in open ... -
Ectopic and normal maxillary canine eruption: maxillary incisor root resorption and interceptive treatment
(Doctoral thesis; Doktorgradsavhandling, 2019-10-25)Ektopisk erupsjon av overkjevens hjørnetenner berører 1-5 prosent av barn, og er en tilstand som kan føre til alvorlige skader på nabotenner samt omfattende tannbehandling. Det vitenskapelige grunnlaget for behandling av ektopiske hjørnetenner er begrenset. Målet med denne PhD-avhandlingen var å skaffe ny kunnskap om omfanget av rotresorpsjon på overkjevens fortenner, den vanligste bivirkningen, ... -
Educational Footprints and Psychosocial Factors in Multicultural Contexts in Arctic Norway. A Cohort and Registry Data Study among Sami and Non-Sami Students, 2003–2012
(Doctoral thesis; Doktorgradsavhandling, 2017-02-17)Utdanning er viktig i alles liv, og i stadig større grad. Formålet med dette forskningsprosjektet var å undersøke sammenhengen mellom utdanningsplaner, skolefrafall i videregående skole og høgere utdanning. Ungdomshelseundersøkelsen i Nord-Norge (UHNN) var en langsgående undersøkelse som fulgte ungdom fra hele Nord-Norge fra 10.klasse og 10 år fram i tid. En rekke forhold ved 10.klassingers liv ... -
Educational inequality in population-based health studies
(Doctoral thesis; Doktorgradsavhandling, 2024-04-04)When comparing groups in the society, one can observed systematic differences in health. The higher the education the group has, the higher the proportion of the group’s member have good health. These differences are known as social inequality in health. Information concerning an individual’s socioeconomic status is often collected through self-administrated questionnaires within epidemiological ... -
The effect of faecal microbiota transplantation in irritabel bowel syndrom. A double blind, randomized placebo controlled single centre study
(Doctoral thesis; Doktorgradsavhandling, 2020-04-17)Irritable bowel syndrome (IBS) is common disorder of the lower gastro intestinal tract associated with a poor quality of life. Revealing the interplay between the microbiota and the host has lead to a better understanding of IBS. A disturbance in the bidirectional communication in the microbiota-gut-brain axis is suggested to be involved in the pathophysiology of IBS. The microbiota in this context ... -
The effect of hypoxaemia on fetal cardiac function
(Doctoral thesis; Doktorgradsavhandling, 2017-08-01)Objectives The objectives were 1. To study the effect of placental embolisation as well as maternal hypoxaemia on fetal left and right ventricular function as reflected by pulsed-wave Doppler-derived myocardial performance index (MPI). 2. To study myocardial systolic and diastolic function of the fetal left and right ventricles using ultrasound speckle tracking technique to measure global strain ... -
The effect of sleeping patterns on mental distress and overweight risk under shifting light conditions in north Norway: Some findings from the Tromsø Study
(Doctoral thesis; Doktorgradsavhandling, 2013-06-28)This dissertation presents the results from three studies that aimed to investigate sleep-wake rhythms and certain health risks in a subarctic community. Sleep timing and duration are influenced by outdoor light, and the darkness of winter has been found to impact the level of mental distress and sleeping problems. Sleep duration, chronotype (preference for being active during the morning or evening) ... -
Effectiveness of interventions and factors of relevance in the treatment of children with conduct problems
(Doctoral thesis; Doktorgradsavhandling, 2008-12-17)The principal aim of this dissertation was to study the effectiveness of treatment of children for severe conduct problems, and to explore factors of relevance for the effects of treatment on these children. In three studies, 127 children aged 4‐8 years and their families participated in a randomized controlled trial of the Incredible Years training sessions that were implemented in two outpatient ... -
Effectiveness of school-based alcohol preventive interventions for adolescents
(Doctoral thesis; Doktorgradsavhandling, 2015-08-21)Early onset of alcohol consumption and early drunkenness, in particular, represent a risk factor for adolescents. Policy-makers and school professionals prioritize preventive alcohol interventions in schools. At the same time, the effectiveness of such interventions has been questioned. The major aim of this dissertation was to evaluate the effectiveness of school-based alcohol preventive programs ... -
The effects of and experiences from participation in GroupCoreDIST- a new, individualized, group-based, physiotherapy intervention for ambulant individuals with multiple sclerosis. A mixed methods study including a randomized controlled trial and a qualitative interview study
(Doctoral thesis; Doktorgradsavhandling, 2020-05-27)<p><i>Introduction: </i>Balance and walking deviations are common in individuals with multiple sclerosis (MS). Individualized physiotherapy is common, however, participation in individualized group physiotherapy is questioned, and needs to be explored in terms of balance and walking-status, effects and user-experiences. <p><i>Methods: </i>This parallel QUAN+QUAL mixed method study included a ... -
Electronically available symptom data – usefulness and feasibility of syndromic surveillance and health care service improvements
(Doctoral thesis; Doktorgradsavhandling, 2013-10-11)Avhandlingen fokuserer på elektronisk tilgjengelige symptom data, nytte og gjennomførbarhet mht sykdomsovervåking og helsetjeneste forbedringer. To hovedspørsmål er adressert: 1. Er et nytt system for overvåkning av smittsomme sykdommer nødvendig, og i så tilfelle, hva er den mest pålitelige og egnede datakilden? Både data hentet fra EPJ-systemer, og pre-konsultasjon symptom-data rapportert av ... -
Embodied uncertainty - Exploring sensorial and existential dimensions of everyday life after cancer
(Doctoral thesis; Doktorgradsavhandling, 2017-11-14)In Norway, as in other countries in the northern hemisphere, an increasing number of people survive after cancer diagnosis and treatment. Earlier studies have shown that life after cancer can be challenging in different ways, which makes it important to gain knowledge about this group to be able to meet their needs in the future. The main objective of this project was to understand the illness ... -
Endocrine-related factors and risk of venous thromboembolism
(Doctoral thesis; Doktorgradsavhandling, 2017-05-31)Even though many environmental and inherited predisposing factors have been associated with venous thromboembolism (VTE), still 30–50% of the events have no obvious provoking factors. There is limited knowledge concerning the association between endocrine-related factors and VTE risk. Therefore we aimed to investigate the relation between hyperglycemia, thyroid function, vitamin D, calcium, ... -
The Endothelial Cell Response to Inflammation, the Functional Role of the Endothelial-enriched Protein KANK3 and the Adipose Tissue Transcriptome
(Doctoral thesis; Doktorgradsavhandling, 2023-10-25)<p>A compilation of three complementary projects explores various facets of endothelial cell biology and transcriptomics, illuminating the intricate dynamics underlying cellular responses to specific stimuli across different tissues. <p>The first project examines how endothelial cells react to the inflammatory molecule tumour necrosis factor (TNF), by studying these cells over time after TNF ... -
Energetics, energy availability and Relative Energy Deficiency in Sport (REDs) in female football players - Methodological perspectives and research implications
(Doctoral thesis; Doktorgradsavhandling, 2024-01-18)<p><i>Background:</i> For athletes, it is imperative that energy intake adequately addresses the total energy requirements inherent to their specific sport. Low energy availability, which is the failure to provide the body with adequate energy to sustain physiological homeostasis, may potentially result in Relative Energy Deficiency in Sport (REDs). This is a syndrome that can have detrimental health ... -
Ensuring valid and reliable data for quality control and research from a clinical registry for spine surgery.
(Doctoral thesis; Doktorgradsavhandling, 2013-11-29)Bakgrunn Behovet for å kvalitetssikre kirurgisk behandling av rygglidelser og utvikle kliniske retningslinjer, er veldokumentert. Derfor ble Nasjonalt kvalitetsregister for ryggkirurgi opprettet. Metodene som brukes må være valide og reliable. Hensikten med avhandlingen var å evaluere målemetodene og å vise hvordan registerdata kan brukes til kvalitetssikring og forskning, slik at pasientbehandlingen ...