Recently it has been suggested that the chronic inflammatory disease psoriasis is more than skin deep, as it has been associated with several comorbid conditions, including diabetes and cardiovascular disease. Increasing prevalence of psoriasis has been observed, possibly due to changes in lifestyle. Within the population-based Tromsø study cohort, we found an increase in the self-reported prevalence ...

This thesis aims to provide more knowledge about psychological and social aspects of cosmetic surgery, in particular what factors are associated with the increased interest in having such surgery oneself. The first paper is angled from a more public health perspective, with focus on what factors predicts whether someone considers having cosmetic surgery in general. In the second paper, the focus ...

Pulsoksymetri er en enkel undersøkelsesmetode for å beregne metningen av oksygen (O2) i arterielt blod (SpO2). Lave verdier kan være indikasjon på hjerte- og/eller lungesykdom. Ingen befolkningsundersøkelser har tidligere sett på oksygenmetning i en voksen befolkning. Avhandlingen er basert på de to befolkningsundersøkelsene, Tromsø 5 (2001/2002) og Tromsø 6 (2007/2008). I disse ble det gjort ...

The overall aim of this dissertation was to expand understanding of the recovery from direct self-harm for adult persons who self-harm through three partial studies. Study I included a theoretical evolutionary concept analysis to clarify the content of the concept self-harm as delineated to the disciplines of medicine and nursing. Studies II and III were interview studies. In study II, mental health ...

Venous thromboembolism (VTE) is a collective term for deep vein thrombosis and pulmonary embolism. VTE is the third most common cardiovascular disease, causing significant morbidity and mortality. The incidence of VTE has been stable or slightly increasing during the last decades, affecting 1-2 per 1000 individuals each year. Up to half of all VTE patients have no obvious cause of the disease. Thus, ...

<p><i>Background:</i> In 1938, J. Alison Glover published a study on incidence of tonsillecto-mies in school children, demonstrating variation in treatment rates across school districts. Consequently, it rates raised questions as to what determines when to treat a patient. After Wennberg and Gittelsohns’ paper ‘Small Area Variations in Health Care Delivery’ was pub-lished in 1973, it became clear ...

Steroid receptor co-activator-3 (SRC-3) is a co-activator that plays important roles in normal physiology and different diseases including cancer. Its activity is regulated by phosphorylation. Serine 857 (S857) is the most frequently reported phosphorylation site of SRC-3. In this work, we examined several kinases that could phosphorylate SRC-3 at S857 and explored the functional outcome incurred ...

Målet med studien Relational insight and user involvement in the context of Norwegian community mental health care. A narrative analysis of service users' stories var å undersøke brukernes innsikt i egen helse og behandling, og legge frem mulige tilnærminger som kan være til hjelp for å anerkjenne og nyttiggjøre seg av brukernes perspektiver i praksishverdagen i distriktspsykiatrien. Studien hadde ...

The need for recruiting and retaining general practitioners (GPs) is expected to increase substantially in the next years, both because of an ageing population and a reform suggesting to shift more resources to primary care. This will not only reinforce the current challenge of recruitment and retention in rural areas, but it may also make it more difficult to recruit and retain GPs in urban areas. ...

<p>Background: Denervation of renal sympathetic nerves (RDN) is a mini-invasive endovascular procedure introduced as an antihypertensive treatment with a potentially beneficial effect on insulin resistance. In this open-label non-randomized study we investigated non-diabetic patients with true treatment-resistant hypertension defined as office systolic blood pressure (BP)>140 mmHg and (mean) daytime ...