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Overweight and Weight Gain Predict Psoriasis Development in a Population-based Cohort

Permanent link
https://hdl.handle.net/10037/10433
DOI
https://doi.org/10.2340/00015555-2530
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Date
2016-09-07
Type
Journal article
Tidsskriftartikkel
Peer reviewed

Author
Danielsen, Kjersti; Wilsgaard, Tom; Olsen, Anne Olaug; Furberg, Anne-Sofie
Abstract
Overweight is a proposed risk factor for psoriasis. How­ever, evidence from prospective studies is limited. The aim of this study was to investigate the association be­tween overweight, weight gain and risk of psoriasis, and potential synergism with smoking, within a population-based cohort including 8,752 individuals followed from 1994 up to 2008. There was a 32% increased odds of psoriasis from a body mass index (BMI) of 27 kg/m2, in multi­variable logistic regression analysis, further increasing to 43% at BMI 28 kg/m2, and to 71% at BMI ≥ 30 kg/m2 in non-smokers. There was a dose-response association between weight gain from age 25 years, with up to 90% higher odds of psoriasis from middle age, independent of weight category. There was no indication of a synergism between overweight and smoking, and no interaction with sex. Overweight and weight gain represent modifiable risk factors that may be targets for primary prevention of psoriasis.
Description
Source: doi: 10.2340/00015555-2530
Publisher
Society for Publication of Acta Dermato-Venereologica
Citation
Danielsen K, Wilsgaard T, Olsen AO, Furberg AS. Overweight and Weight Gain Predict Psoriasis Development in a Population-based Cohort. Acta Dermato-Venereologica. 2016
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  • Artikler, rapporter og annet (samfunnsmedisin) [1514]

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