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Open discectomy vs microdiscectomy for lumbar disc herniation - a protocol for a pragmatic comparative effectiveness study

Permanent link
https://hdl.handle.net/10037/10578
DOI
https://doi.org/10.12688/f1000research.9015.1
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Date
2016-09-02
Type
Journal article
Tidsskriftartikkel
Peer reviewed

Author
Sørlie, Andreas; Gulati, Sasha; Giannadakis, Charalampis; Carlsen, Sven Magnus; Salvesen, Øyvind; Nygaard, Øystein Petter; Solberg, Tore
Abstract
Introduction:
Since the introduction of lumbar microdiscectomy in the 1970’s, many studies have attempted to compare the effectiveness of this method with that of standard open discectomy with conflicting results. This observational study is designed to compare the relative effectiveness of microdiscectomy (MD) with open discectomy (OD) for treating lumbar disc herniation, -within a large cohort, recruited from daily clinical practice.
Methods and analysis:
This study will include patients registered in the Norwegian Registry for Spine Surgery (NORspine). This clinical registry collects prospective data, including preoperative and postoperative outcome measures as well as individual and demographic parameters. The primary outcome is change in Oswestry disability index between baseline and 12 months after surgery. Secondary outcome measures are improvement of leg pain and changes in health related quality of life measured by the Euro-Qol-5D between baseline and 12 months after surgery, complications to surgery, duration of surgical procedures and length of hospital stay.
Description
Source: doi: 10.12688/f1000research.9015.1
Publisher
F1000Research
Citation
Sørlie A, Gulati S, Giannadakis C et al. Open discectomy vs microdiscectomy for lumbar disc herniation - a protocol for a pragmatic comparative effectiveness study [version 1; referees: 2 approved]. F1000Research 2016, 5:2170 (doi: 10.12688/f1000research.9015.1)
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