Artikler, rapporter og annet (samfunnsmedisin): Nye registreringer
Viser treff 161-180 av 1471
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Interpolation, dés-interpolation, ré-interpolation. Le Tristan en prose et l'Agravain
(Chapter; Bokkapittel, 2021)Vers la fin de la séquence d’épisodes repris à l’Agravain qui se trouvent interpolés dans certains manuscrits du Tristan en prose, les chevaliers partis en quête de Lancelot retournent à la cour du roi Arthur à Camaalot. Ils rentrent non seulement avec leur héros, mais encore avec leurs histoires : une fois tous confortablement installés – toute armure dûment enlevée – le roi invite ses chevaliers ... -
Forty Years of Arctic Primary Care Research on the Early Diagnosis of Cancer
(Chapter; Bokkapittel, 2021)Usually, before a patient with cancer can be treated in a hospital, a general practitioner (GP) must suspect the diagnosis and refer the patient. GPs often worry that they could have done better for some of their cancer patients. Had there been an unreasonable delay of diagnosis? In the arctic, rural/urban city of Tromsø, this question became the subject of several scientific articles. Symptoms was ... -
Signals of Death - Post-Diagnostic Single Gene Expression Trajectories in Breast Cancer - A Proof of Concept
(Chapter; Bokkapittel, 2020-12-08)Using the time-dependent dynamics of gene expression from immune cells in blood, we aimed to explore single gene expression trajectories as biomarkers for death after a diagnosis of breast cancer introducing a new statistical method denoted Difference in Time Development Statistics (DTDS). This shows as proof of principle that the gene expression profiles from immune cells in blood differed in the ... -
Treatment Preferences in Young Adults with Moderate to Severe Psoriasis: A Qualitative Study from the Nordic Countries
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-15)Introduction - The purpose of this study is to explore treatment preferences and identify patient characteristics in young bio-naive adults with moderate to severe psoriasis in the Nordic countries (Norway, Finland, Sweden, and Denmark).<p> <p>Methods - Patients were 18–45 years old and bio-naive but referred for biologic treatment of moderate to severe psoriasis. Patients were included at eight ... -
Lung cancer risk discrimination of prediagnostic proteomics measurements compared with existing prediction tools
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-01)Background: We sought to develop a proteomics-based risk model for lung cancer and evaluate its risk-discriminatory performance in comparison with a smoking-based risk model (PLCOm2012) and a commercially available autoantibody biomarker test.<p><p>Methods: We designed a case-control study nested in 6 prospective cohorts, including 624 lung cancer participants who donated blood samples at most 3 ... -
Decisions on sick leave certifications for acute airways infections based on vignettes: A cross-sectional survey of GPs in Norway and Poland
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011-02-17)Objective. To explore whether frequency and duration of sick-leave certifi cation for acute airway infections differ between general practitioners (GPs) in Poland and Norway. Design . Cross-sectional survey. Setting. Educational courses for GPs. Intervention. We used a questionnaire with four vignettes presenting patients with symptoms consistent with pneumonia, sinusitis, common cold, and ... -
Leadership in rural medicine: The organization on thin ice?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011-04-28)Objective. To explore the personal experiences of and conceptions regarding leading rural primary care in Northern Norway. Design. Qualitative content analysis of focus-group interviews. Setting. Lead primary care physicians in the three northernmost counties. Subjects. Four groups with 22 out of 88 municipal lead physicians in the region. Results. Three main categories were developed and bound ... -
Choice is not the issue. The misrepresentation of healthcare in bioethical discourse
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011-03-17)The principle of respect for autonomy has shaped much of the bioethics' discourse over the last 50 years, and is now most commonly used in the meaning of respecting autonomous choice. This is probably related to the influential concept of informed consent, which originated in research ethics and was soon also applied to the field of clinical medicine. But while available choices in medical research ... -
Pizza made healthy – an epidemiological cookbook
(Conference object; Konferansebidrag, 2021) -
Numbers, tables and statistics
(Conference object; Konferansebidrag, 2021)<p>The old “Lofoten Post” building sits at the end of the dock in Svolvær as an empty shell, ready for the winter storms to seal its destiny. Everything that reminds of newspaper production is stripped from the building, only dents from the editor’s desk can still be seen on the floor. Wait! A stack of newspapers, filled with tables of fishery, trade, crimes, and everything else that transforms small ... -
The 99% accuracy club
(Conference object; Konferansebidrag, 2021)<p>Melanoma Classification - a 10,000$ competition. For the 2020 Melanoma Classification competition hosted by kaggle, 33,126 images were made available for training (of which 2% were melanomas), and an additional 10,982 were used for final ranking of the 3,308 teams who entered the competition with eyes on the 10,000$ prize. The task was simple: provide a probability for melanoma (deadly skin cancer) ... -
Functional transcriptomics in 17 year-old blood samples? Yes, we can! -Long-term RNA in situ stability in blood samples collected in PAXgene Blood RNA Tubes (PreAnalytiX GmbH) collected in 2003
(Conference object; Konferansebidrag, 2021)Analysis of blood RNA transcription profiles is hindered by ex vivogene expression changes, as well as degradation and loss of RNA over time during specimen transportation and storage. The PAXgeneBlood RNA System was developed by PreAnalytiXto overcome these problems. So far, quality control data has shown that the PAXgene Blood RNA System stabilizes and preserves RNA in blood specimens for up to ... -
Tanker rundt primærhelseteam
(Conference object; Konferansebidrag, 2018) -
Effects of Interventions to Prevent Work-Related Asthma, Allergy, and Other Hypersensitivity Reactions in Norwegian Salmon Industry Workers (SHInE): Protocol for a Pragmatic Allocated Intervention Trial and Related Substudies
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-07)Background: Workers in the salmon processing industry have an increased risk of developing respiratory diseases and other hypersensitivity responses due to occupational exposure to bioaerosols containing fish proteins and microorganisms, and related allergens. Little is known about effective measures to reduce bioaerosol exposure and about the extent of skin complaints among workers. In addition, ... -
C-reactive protein point-of-care testing for safely reducing antibiotics for acute exacerbations of chronic obstructive pulmonary disease: The PACE RCT
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03)Background - Most patients presenting with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in primary care are prescribed antibiotics, but these may not be beneficial, and they can cause side effects and increase the risk of subsequent resistant infections. Point-of-care tests (POCTs) could safely reduce inappropriate antibiotic prescribing and antimicrobial resistance.<p> ... -
Association of Mediterranean diet with survival after breast cancer diagnosis in women from nine European countries: results from the EPIC cohort study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-26)Background - The Mediterranean diet has been associated with lower risk of breast cancer (BC) but evidence from prospective studies on the role of Mediterranean diet on BC survival remains sparse and conflicting. We aimed to investigate whether adherence to Mediterranean diet prior to diagnosis is associated with overall and BC-specific mortality.<p> <p>Methods - A total of 13,270 incident breast ... -
Educational interventions to ensure provision of doctors in rural areas - a systematic review
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-10)Introduction: Recruiting doctors in rural areas is challenging. Various educational interventions have been introduced in many countries. This study aimed to explore undergraduate medical education interventions introduced to recruit doctors to rural areas, and the results of these interventions. Methods: We undertook a systematic search using search words 'rural', 'remote', 'workforce', 'physicians', ... -
13-Type HPV DNA Test versus 5-Type HPV mRNA Test in Triage of Women Aged 25–33 Years with Minor Cytological Abnormalities–6 Years of Follow-Up
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-25)Background: A specific, cost-effective triage test for minor cytological abnormalities is essential for cervical cancer screening among younger women to reduce overmanagement and unnecessary healthcare utilization. We compared the triage performance of one 13-type human papillomavirus (HPV) DNA test and one 5-type HPV mRNA test. Methods: We included 4115 women aged 25–33 years with a screening ... -
Lipid Levels During Adult Lifetime in Men and Women With and Without a Subsequent Incident Myocardial Infarction: A Longitudinal Analysis of Data From the Tromsø Study 1974 to 2016
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-14)Background - The atherosclerotic effect of an adverse lipid profile is assumed to accumulate throughout life, leading to increased risk of myocardial infarction (MI). Still, little is known about age at onset and duration of unfavorable lipid levels before MI.<p> <p>Methods and Results - Longitudinal data on serum lipid levels for 26 130 individuals (50.5% women, aged 20–89 years) were obtained ... -
Evaluation of Synthetic Categorical Data Generation Techniques for Predicting Cardiovascular Diseases and Post-Hoc Interpretability of the Risk Factors
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-23)Machine Learning (ML) methods have become important for enhancing the performance of decision-support predictive models. However, class imbalance is one of the main challenges for developing ML models, because it may bias the learning process and the model generalization ability. In this paper, we consider oversampling methods for generating synthetic categorical clinical data aiming to improve the ...