Viser treff 41-60 av 1522

    • Proton therapy versus conventional radiotherapy for the treatment of cavernous sinus benign meningioma, a randomized controlled phase III study protocol (COG-PROTON-01) 

      Lesueur, Paul; Clarisse, Benedicte; Lequesne, Justine; Licaj, Idlir; Feuvret, Loic; Stefan, Dinu; Ricard, Damien; Noel, Georges; Balosso, Jacques; Lange, Marie; Capel, Aurelie; Durand-Zaleski, Isabelle; Castera, Marie; Legrand, Berenice; Goliot, Nicolas; Hedou, Camille; Grellard, Jean Michel; Valable, Samuel (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-12-30)
      Background Proton therapy (PRT) is an innovative radiotherapeutic modality for the treatment of cancer with unique ballistic properties. The depth-dose distribution of a proton beam reduces exposure of healthy tissues to radiations, compared with photon-therapy (XRT). To date, only few indications for proton-therapy, like pediatric cancers, chordomas, or intra-ocular neoplasms, are reimbursed by ...
    • “They were sort of in the room with me”: a qualitative study about callers’ experience of video streaming during medical emergency calls 

      Hjortdahl, Magnus; Häikiö, Kristin; Kramer-Johansen, Jo; Idland, Siri (Journal article; Tidsskriftartikkel; Peer reviewed, 2025-01-08)
      Background During the recent years, emergency services in several countries have integrated video streaming into medical emergency calls, and research on the topic has gained increased focus. Video streaming during medical emergency calls may change dispatcher’s perspective of the call and can be a helpful tool for supervising bystanders’ first aid. Little research exists, however, about the ...
    • Deep learning-based classification of breast cancer molecular subtypes from H&E whole-slide images 

      Tafavvoghi, Masoud; Sildnes, Anders; Shvetsov, Nikita; Rakaee, Mehrdad; Bongo, Lars Ailo; Busund, Lill-Tove Rasmussen; Møllersen, Kajsa (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-11-17)
      Classifying breast cancer molecular subtypes is crucial for tailoring treatment strategies. While immunohistochemistry (IHC) and gene expression profiling are standard methods for molecular subtyping, IHC can be subjective, and gene profiling is costly and not widely accessible in many regions. Previous approaches have highlighted the potential application of deep learning models on hematoxylin ...
    • The governance of the SAMINOR Study and integration of the CARE principles 

      Melhus, Marita; Broderstad, Ann Ragnhild (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-11-13)
      The SAMINOR Study represents a unique data collection on health and diseases among the multiethnic population – including the Sámi population in Norway – making it a case study for discussing Sámi research data governance in a health context. This article describes how Sámi interests and needs in the SAMINOR Study are governed by two steps of a research application review process consisting of the ...
    • Longitudinal cholesterol trends across socioeconomic groups in Norway: the influence of lipid-lowering drugs in the population-based Tromsø Study 1994–2016 

      Vo, Chi Quynh; Wilsgaard, Tom; Samuelsen, Per-Jostein; Mathiesen, Ellisiv B.; Sommerseth, Hilde Leikny; Eggen, Anne Elise; Wisløff, Torbjørn (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-12-26)
      Objectives There is limited evidence regarding the impact of lipid-lowering drugs (LLDs) on the socioeconomic gradient in a longitudinal perspective. The study investigates the longitudinal socioeconomic gradient in total cholesterol levels and whether this is affected by the use of LLDs.<p> <p>Design Population-based cohort study. <p>Setting Sample from adult inhabitants of Tromsø municipality, ...
    • Combined prediagnostic lifestyle factors and survival of breast, colorectal and lung cancer in the Norwegian Women and Cancer (NOWAC) study: a prospective cohort study 

      Chen, Sairah Lai Fa; Borch, Kristin Benjaminsen; Sandanger, Torkjel Manning; Tinmouth, Jill; Braaten, Tonje Bjørndal; Nøst, Therese Haugdahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-11-27)
      Background With improvements in cancer treatment and early detection, the number of people living with cancer is increasing.<p> <p>Objective This study aimed to investigate the association between combined prediagnostic lifestyle factors, assessed by a Healthy Lifestyle Index (HLI) score, and mortality among women diagnosed with breast cancer (BC), colorectal cancer (CRC) and lung cancer ...
    • Alcohol and cause-specific mortality in Russia: the Know Your Heart Study 2015–23 

      Mitkin, Nikita Andreevich; Brenn, Tormod Ola; Unguryanu, Tatiana N.; Malyutina, Sofia; Cook, Sarah; Kudryavtsev, Alexander V. (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-11-12)
      <p>Background - Alcohol-related mortality in Russia exceeds the world average and presents a critical public health concern. This study assesses the impact of alcohol consumption levels on mortality and investigates mortality predictors among Russians, including people treated for alcohol-related diagnoses (narcology patients). <p>Methods - We examined 2629 men and women aged 35–69 years who ...
    • Prescription of benzodiazepines and antidepressants among Sami and non-Sami — How childhood violence shapes prescription patterns: the SAMINOR 2 questionnaire survey and the Norwegian prescription database 

      Eriksen, Astrid Margrethe Anette; Melhus, Marita; Broderstad, Ann Ragnhild; Smylie, Janet (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-11-07)
      Background - Medication for mental health problems represents a significant proportion of overall medication use and the prescription of psychotropic medicine has increased in many western countries over the last decades. Childhood violence (CV) is strongly associated with mental health problems, which in turn may increase the likelihood of being prescribed psychotropic medication. However, the ...
    • Work-leave rotation among general practitioners in Norwegian municipalities 

      Prestgaard, Erik Edvard; Fosse, Anette; Abelsen, Birgit; Harbitz, Martin Bruusgaard (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-11-19)
      Bakgrunn - Flere kommuner har innført rotasjonsordning (nordsjøturnus) for allmennleger, der legene gjennom året veksler mellom arbeidsperioder og friperioder. Vi har undersøkt utbredelsen av, årsaker til, innhold i og erfaringer med denne arbeidsformen.<p> <p>Materiale og metode - Vi har gjennomført en flerkasusstudie med data fra Statistisk sentralbyrå, fastlegeregisteret, kommunale dokumenter, ...
    • Menopausal hormone therapy and incidence, mortality, and survival of breast cancer subtypes: a prospective cohort study 

      Busund, Marit Katinka; Ursin, Giske; Lund, Tore Eiliv; Chen, Sairah Lai Fa; Rylander, Karin Charlotta Maria (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-11-04)
      Background Menopausal hormone therapy (MHT) is associated with an increased risk of postmenopausal breast cancer, predominantly the luminal A-like subtype. The impact of MHT on deaths from breast cancer subtypes is less understood. This study aimed to explore associations between MHT use and the incidence, mortality, and survival of intrinsic-like breast cancer subtypes.<p> <p>Methods Data from ...
    • Social isolation and loneliness and their association with all-cause mortality. A population-based longitudinal study in Norway: The Tromsø Study 1994–2023 

      Løvsletten, Ola; Brenn, Tormod Ola (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-11-20)
      Objectives - Loneliness and social isolation are associated with increased mortality, but few studies have assessed this association over long time in young adults.<p> <p>Methods - The study sample comprised 9061 women and 8735 men aged 25 to 69 years who participated in the Tromsø4 survey (1994–95, baseline) of the Tromsø Study, Norway. A subset of the study sample also attended the Tromsø5 ...
    • Oppsummering fra brukerverksted for folkehelseforskning 

      Torgersen, Tone; Unnerud, Karoline; Ariansen, Inger; Grimsgaard, Sameline (Research report; Forskningsrapport, 2023)
    • Spectrum of COVID-19 cases in Arkhangelsk, Northwest Russia: Findings from a population-based study linking serosurvey, registry data, and self-reports of symptoms 

      Krieger, Ekaterina Anatoljevna; Kudryavtsev, Alexander V; Sharashova, Ekaterina; Samodova, Olga; Kontsevaya, Anna; Postoev, Vitaly A. (Journal article; Tidsskriftartikkel, 2024-10-11)
      <p><i>Introduction</i> The spectrum of COVID-19 manifestations makes it challenging to estimate the exact proportion of people who had the infection in a population, with the proportion of asymptomatic cases likely being underestimated. We aimed to assess and describe the spectrum of COVID-19 cases in a sample of adult population aged 40–74 years in Arkhangelsk, Northwest Russia, a year after the ...
    • Impact of the diagnostic label for a low-risk prostate lesion: protocol for two online factorial randomised experiments 

      Bullen, James; Nickel, Brooke; McCaffery, Kirsten; Wilt, Timothy J.; Smith, Jenna; Boroumand, Farzaneh; Parker, Lisa; Millar, Jeremy; Brodersen, John; Dahm, Philipp; Delahunt, Brett; Varma, Murali; Glasziou, Paul; Warden, Andrew; Diller, Lawrence; Billington, Larry; van Rensburg, Christo; Bell, Katy (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-08-09)
      Introduction - Many types of prostate cancer present minimal risk to a man’s lifespan or well-being, but existing terminology makes it difficult for men to distinguish these from high-risk prostate cancers. This study aims to explore whether using an alternative label for low-risk prostate cancer influences management choice and anxiety levels among Australian men and their partners.<p> <p>Methods ...
    • Longitudinal lung function trajectories in response to azithromycin therapy for chronic lung disease in children with HIV infection: a secondary analysis of the BREATHE trial 

      Madanhire, Tafadzwa; McHugh, Grace; Simms, Victoria; Ngwira, Lucky; Gonzalez-Martinez, Carmen; Semphere, Robina; Moyo, Brewster; Calderwood, Claire; Nicol, Mark; Bandason, Tsitsi; Odland, Jon Øyvind; Rehman, Andrea M.; Ferrand, Rashida A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-07-12)
      Background - Chronic lung disease (CLD) is common among children with HIV (CWH) including in those taking antiretroviral therapy (ART). Azithromycin has both antimicrobial and anti-inflammatory effects and has been effective in improving lung function in a variety of lung diseases. We investigated lung function trajectories among CWH with CLD on ART enrolled in a randomized controlled trial of ...
    • Sámi community perspectives on the COVID-19 pandemic: a mixed methods case study in Arctic Sweden 

      Stoor, Jon Petter Anders; Sedholm, Oscar; San Sebastián, Miguel; Nilsson, Lena Maria (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-06-25)
      The COVID-19 pandemic posed a grave threat not only to Indigenous people’s health and well-being, but also to Indigenous communities and societies. This applies also to the Indigenous peoples of the Arctic, where unintentional effects of public health actions to mitigate the spread of virus may have long-lasting effects on vulnerable communities. This study aim was to identify and describe Sámi ...
    • Exploring views among Norwegian Sámi regarding gambling and gambling treatment 

      Devold, Marte Reikvam; Spein, Anna Rita; Barua, Pia; Indset, Marie Pedersen; Syvertsen, Andre; Pallesen, Ståle (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-09-19)
      Aim: To explore gambling in the indigenous Sámi culture by studying thoughts, ideas and attitudes towards gambling among Sámi and people living in majority Sámi areas with knowledge of the culture. <p> <p>Methods: The topic was investigated in an inductive thematic analysis of semi-structured interviews with 14 people (n = 13 self-reported Sámi ethnicity). <p> <p>Results: The majority of the ...
    • Nutritional quality of diet characterized by the Nutri-Score profiling system and cardiovascular disease risk: a prospective study in 7 European countries 

      Deschasaux-Tanguy, Mélanie; Huybrechts, Inge; Julia, Chantal; Hercberg, Serge; Sarda, Barthélémy; Fialon, Morgane; Arnault, Nathalie; Srour, Bernard; Kesse-Guyot, Emmanuelle; Fezeu, Léopold K.; Biessy, Carine; Casagrande, Corinne; Hemon, Bertrand; Weiderpass Vainio, Elisabete; Pinho, Maria G.M.; Murphy, Neil; Freisling, Heinz; Ferrari, Pietro; Tjønneland, Anne; Nielsen Petersen, Kristina Elin; Katzke, Verena; Kaaks, Rudolf; Schulze, Matthias B.; Masala, Giovanna; Pala, Valeria; Panico, Salvatore; Ricceri, Fulvio; Verschuren, W.M.Monique; Boer, Jolanda M.A.; van der Schouw, Yvonne T.; Skeie, Guri; Agudo, Antonio; Molina-Montes, Esther; Huerta, José María; Moreno-Iribas, Conchi; Ericson, Ulrika; Sonestedt, Emily; Strid, Anna; Oskarsson, Viktor; Tong, Tammy Y.N.; Heath, Alicia K.; Aglago, Elom K.; Danesh, John; Riboli, Elio; Gunter, Marc J.; Touvier, Mathilde (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-11)
      Background - Nutri-Score is a scientifically validated 5-color front-of-pack nutrition label reflecting the nutrient profile of foods. It has been implemented in several European countries on a voluntary basis, pending the revision of the European labeling regulation. Hence, scientific evidence is needed regarding the ability of the nutrient profile underlying the Nutri-Score (uNS-NPS, 2023-updated ...
    • How well does a single blood sample represent long-term exposure for epidemiological studies of PFOA among men in the general population? 

      Bartell, Scott M.; Purdue, Mark P.; Rhee, Jongeun; Nøst, Therese Haugdahl; Rusiecki, Jennifer; Steenland, Kyle (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-10-05)
      Many epidemiological studies use a single blood sample per participant to assess exposure, but it is unclear how well a single sample represents longer term exposure. We performed a simulation study using summary statistics for repeated serum PFOA measurements from several previous studies in men to generate plausible serum concentrations over time, taking within-subject correlations into account. ...
    • Effect of pharmacological treatment of attention-deficit/hyperactivity disorder on later psychiatric comorbidity: a population-based prospective long-term study 

      Lyhmann, Ingvild; Widding-Havnerås, Tarjei; Bjelland, Ingvar; Markussen, Simen; Elwert, Felix; Chaulagain, Ashmita; Mykletun, Arnstein; Halmøy, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-09-19)
      Background Psychiatric comorbidity is frequent among persons with attention-deficit/hyperactivity disorder (ADHD). Whether pharmacological treatment of ADHD influences the incidence of psychiatric comorbidity is uncertain.<p> <p>Objective To investigate associations and causal relations between pharmacological treatment of ADHD and incidence of subsequent comorbid psychiatric diagnoses. <p>Methods ...