• Dissemination of Piscine orthoreovirus-1 (PRV-1) in Atlantic Salmon (Salmo salar) during the Early and Regenerating Phases of Infection 

      Dhamotharan, Kannimuthu; Bjørgen, Håvard; Malik, Muhammad Salman; Nyman, Ingvild Berg; Markussen, Turhan Ali Dadasbilge; Dahle, Maria; Koppang, Erling Olaf; Wessel, Øystein; Rimstad, Espen (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-20)
      <i>Piscine orthoreovirus-1</i> (PRV-1) can cause heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (<i>Salmo salar</i>), but the line of events from infection, pathologic change, and regeneration has not been thoroughly described. In this study, the cellular localization and variation of PRV-1 RNA and protein levels were analyzed at different times post-exposure in experimentally ...
    • The teleost polymeric Ig receptor counterpart in ballan wrasse (Labrus bergylta) differs from pIgR in higher vertebrates 

      Etayo, Angela; Bjørgen, Håvard; Koppang, Erling Olaf; Hordvik, Ivar (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-13)
      As mucosal barriers in fish are the main sites where pathogens are encountered, mucosal immunity is crucial to avoid infection in the aquatic environment. In teleost fish, immunoglobulins are present in gut, gill and skin mucus, although not in the same amounts as in higher vertebrates. In mammals, the poly-Ig receptor (pIgR) is synthesized in epithelial cells and mediates the active transport ...