• 3-Chloro-N′-(2-hydroxybenzylidene) benzohydrazide: An LSD1-Selective Inhibitor and Iron-Chelating Agent for Anticancer Therapy 

      Sarno, Federica; Papulino, Chiara; Franci, Gianluigi; Andersen, Jeanette hammer; Cautain, Bastien; Melardo, Colombina; Altucci, Lucia; Nebbioso, Angela; Andersen, Jeanette H. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-07)
      Despite the discovery and development of novel therapies, cancer is still a leading cause of death worldwide. In order to grow, tumor cells require large quantities of nutrients involved in metabolic processes, and an increase in iron levels is known to contribute to cancer proliferation. Iron plays an important role in the active site of a number of proteins involved in energy metabolism, DNA ...
    • Accounting for Uncertainties in Biodiversity Estimations: A New Methodology and Its Application to the Mesopelagic Sound Scattering Layer of the High Arctic 

      Herrmann, Bent; Cerbule, Kristine; Brčić, Jure; Grimaldo Vela, Eduardo Enrique; Geoffroy, Maxime; Daase, Malin; Berge, Jørgen (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-27)
      Measures of biological diversity (biodiversity) are important for monitoring the state of ecosystems. Several indices and methods are used to describe biodiversity from field observations. Marine faunal biodiversity is often quantified based on analysis of samples collected using a trawl during research surveys. To monitor spatial and temporal changes in biodiversity between surveys, samples are ...
    • Adding zooplankton to the OSMAC toolkit: Effect of grazing stress on the metabolic profile and bioactivity of a diatom 

      Osvik, Renate Døving; Ingebrigtsen, Richard Andre; Norrbin, Fredrika; Andersen, Jeanette Hammer; Eilertsen, Hans Christian; Hansen, Espen Holst (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-03)
      “One strain many compounds” (OSMAC) based approaches have been widely used in the search for bioactive compounds. Introducing stress factors like nutrient limitation, UV-light or cocultivation with competing organisms has successfully been used in prokaryote cultivation. It is known that diatom physiology is affected by changed cultivation conditions such as temperature, nutrient concentration and ...
    • Adjusting the Fitting of Fluorescence-Based Dose-Response Kinase Inhibition Assay to Account for Fluorescent Inhibitors 

      Petit, Guillaume Axel (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-11)
      Fluorescence is routinely used to monitor kinase inhibition in commercial assays. Occasionally fluorescent compounds can interfere with the fluorescent reading. To address this issue, the problematic data are usually truncated to improve the fit, however, this approach raises ethical and reproducibility concerns. Instead, it is suggested to adjust the fitting formula, to account for the autofluorescence ...
    • Adjuvant activity of fish type I interferon shown in a virus DNA vaccination model 

      Chang, Chia Jung; Sun, Baojian; Robertsen, Børre (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-04-09)
      There is a need for more efficient vaccines to combat viral diseases of Atlantic salmon and other farmed fish. DNA vaccines are highly effective against salmonid rhabdoviruses, but have shown less effect against other viruses. In the present work we have studied if type I IFNs might be used as adjuvants in fish DNA vaccines. For this purpose we chose a DNA vaccine model based on the hemagglutin ...
    • Adjuvants and immunostimulants in fish vaccines: Current knowledge and future perspectives. 

      Tafalla, C; Bøgwald, Jarl; Dalmo, Roy Ambli (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Vaccination is the most adequate method to control infectious diseases that threaten the aquaculture industry worldwide. Unfortunately, vaccines are usually not able to confer protection on their own; especially those vaccines based on recombinant antigens or inactivated pathogens. Therefore, the use of adjuvants or immunostimulants is often necessary to increase the vaccine efficacy. Traditional ...
    • Administration of watermelon rind powder to Nile tilapia (Oreochromis niloticus) culture under biofloc system: Effect on growth performance, innate immune response, and disease resistance 

      Doan, Hien Van; Lumsangkul, Chompunut; Hoseinifar, Seyed Hossein; Hung, Tran Quang; Stejskal, Vlastimil; Ringø, Einar; Dawood, Mahmoud A.O.; Esteban, Maria Ángeles (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-07)
      An eight-week experiment was performed to assess the effectiveness of watermelon rind powder (WMRP) on growth efficiency, immunity, and disease resistance of Nile tilapia, <i>O. niloticus</i>. Three hundred fish (17.14 ± 0.12 g) were fed five diets; 0 (Diet 1- control), 20 g kg<sup>−1</sup> WMRP (Diet 2), 40 g kg<sup>−1</sup> WMRP (Diet 3), 80 g kg<sup>−1</sup> WMRP (Diet 4), and 160 g kg<sup>−1</sup> ...
    • Advancing research for the management of long-lived species: A case study on the Greenland Shark 

      Edwards, Jena E.; Hiltz, Elizabeth; Broell, Franziska; Bushnell, Peter G.; Campana, Steven E.; Christiansen, Jørgen Schou; Devine, Brynn M.; Gallant, Jeffrey J.; Hedges, Kevin J.; MacNeil, M. Aaron; McMeans, Bailey C.; Nielsen, Julius; Præbel, Kim; Skomal, Gregory B.; Steffensen, John Fleng; Walter, Ryan P.; Watanabe, Yuuki Y.; VanderZwaag, David L.; Hussey, Nigel E. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-02)
      Long-lived species share life history traits such as slow growth, late maturity, and low fecundity, which lead to slow recovery rates and increase a population’s vulnerability to disturbance. The Greenland shark (Somniosus microcephalus) has recently been recognized as the world’s longest-lived vertebrate, but many questions regarding its biology, physiology, and ecology remain unanswered. Here we ...
    • Advection-diffusion models of spiny lobster Palinurus gilchristi migrations for use in spatial fisheries management 

      Santos, Jorge; Rouillard, Denis; Groeneveld, Johan C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-02-17)
    • Advice on fishing opportunities for Barents Sea capelin in 2024 — ICES subareas 1 and 2 excluding Division 2.a west of 5°W 

      Howell, Daniel; Nielsen, Anders; Stock, Brian; Ono, Kotaro; Clain, Laura; Fossheim, Maria; Wenneck, Thomas de Lange; Harbitz, Alf; Rodriguez, Alfonso Pérez; Iriondo, Ane; Staby, Arved; Bogstad, Bjarte; Husson, Berengere; Marshall, C. Tara; Tranang, Caroline Aas; Johannesen, Edda; Vozgirdas, Eduardas; Eriksen, Elena; Eidset, Elise; Hallfredsson, Elvar H.; Berg, Erik; Skaret, Georg; Höffle, Hannes; Jacobsen, Jan Arge; Stiansen, Jan Erik; Godiksen, Jane Aanestad; Janusz, Jerzy; Fall, Johanna Jennifer Elisabeth; Trochta, John Tyler; Gondra, Jon Ruiz (Research report; Forskningsrapport, 2023-10-16)
    • Aktuelle sykdomsutbrudd og diagnoser 

      Grønbech, Synne; Erkinharju, Toni; Hansen, Miroslava (Journal article; Tidsskriftartikkel; Peer reviewed, 2020)
      Aktuelle diagnoser, «nye» sykdommer og spesielle tilfeller har i mange år blitt presentert under vignetten «Aktuelle sykdomsutbrudd og diagnoser fra Veterinærinstituttet, Mattilsynet og NMBU Veterinærhøgskolen». Redaksjonen er av den oppfatning at dette er nyttig og lett tilgjengelig informasjon som bidrar til å opprettholde medlemmenes kunnskap om utviklingen innen diagnostikk og overvåkning av ...
    • Aldri mer 18. april! 

      Finstad, Bjørn-Petter; Holm, Petter (Chronicle; Kronikk, 2013-04-18)
      Den 18. april 1989 er et viktig vendepunkt i norsk fiskerihistorie. Det var den dagen Fiskeridepartementet stoppet kystflåtens fiske etter torsk nord for 62. breddegrad - midt i den tradisjonelle sesongen. Reaksjonene lot ikke vente på seg. Historiens første totalforbud mot å fiske torsk var “et sjokk til dyp ettertanke”, het det i Fiskeribladet.
    • Algal amendment enhances biogenic methane production from coals of different thermal maturity 

      Platt, George A.; Davis, Katherine J.; Schweitzer, Hannah; Smith, Heidi J.; Fields, Matthew W.; Barnhart, Elliott P.; Gerlach, Robin (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-10)
      The addition of small amounts of algal biomass to stimulate methane production in coal seams is a promising low carbon renewable coalbed methane enhancement technique. However, little is known about how the addition of algal biomass amendment affects methane production from coals of different thermal maturity. Here, we show that biogenic methane can be produced from five coals ranging in rank ...
    • Allelic losses and gains during translocations of a high conservation value fish, Coregonus lavaretus 

      Præbel, Kim; Bean, Colin; Dodd, Jennifer A.; Etheridge, Elizabeth C.; Gowans, Andrew R. D.; Knudsen, Rune; Lyle, Alexander A.; Maitland, Peter S.; Winfield, Ian J.; Adams, Colin E. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-09)
      <ol type="1"> <li>The use of translocations to establish new or ‘refuge’ populations for species with high conservation value is controversial but widely used in conservation management. One of the risks of this approach is that an establishing population does not adequately capture the genetic diversity of the donor gene pool. This effect, rarely examined, is tested here.</li> <li>In this study ...
    • Allochrony as a potential driver for reproductive isolation in adaptive radiations of European whitefish ecomorphs 

      Bitz-Thorsen, Julie; Häkli, Katja; Bhat, Shripathi; Præbel, Kim (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-29)
      In northern Fennoscandian lakes, monophylogenetic lineages of postglacial fishes are radiating into several adaptive forms, but the speciation process is still at an incipient stage. The speciation process has received increased attention over the years, but the underlying mechanisms and drivers are still debated and poorly understood. European whitefish (<i>Coregonus lavaretus</i> [L.]) is the most ...
    • Alt på land 

      Svorken, Marianne; Høgstad, Maria Alfredsen; Esaiassen, Margrethe; Nøstvold, Bjørg Helen (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-31)
      Mye av restråstoffet som oppstår om bord på norske torsketrålere blir ikke ført til land. I denne artik-kelen drøfter vi hvorfor fartøy i akkurat denne gruppen ikke utnytter restråstoffet bedre. Gjennom en kvalitativ tilnærming supplert med tallanalyser fra landingsstatistikken diskuteres mulige forklarings-variabler og løsninger. Våre resultater viser at ivaretakelse av restråstoff forbindes med ...
    • Alternative bait trials in the Barents Sea snow crab fishery 

      Araya-Schmidt, Tomas; Olsen, Leonore; Rindahl, Lasse; Larsen, Roger B.; Winger, Paul D. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-05-13)
      Commercial harvesting of snow crab (<i>Chionoecetes opilio</i>) in the Barents Sea started in 2012 by Norwegian fishing vessels. This new fishery has significant bait requirements, representing an emerging conservation challenge. In this study, we evaluate the performance of five alternative (natural) baits manufactured from the waste stream of existing and sustainably managed harp seal (<i>Pagophilus ...
    • Alternative materialer til plast brukt i snurrevadtau og trålmatter 

      Alvestad, Anja Helene; Grimaldo, Eduardo; Lilleng, Grethe; Syversen, Tore; Vollstad, Jørgen; Johnsen, Hilde Rødås (Research report; Forskningsrapport, 2023-10-30)
      Dette prosjektet studerte ulike løsninger for å redusere effekten av slitasje fra fossilbasert, ikke-nedbrytbare plastmaterialer som brukes i snurrevad og trålmatter. Prosjektet testet ulike natur-, syntetiske og biologisk nedbrytbare materialer i laboratorium og i felt. Prosjektet kvantifiserte og sannsynliggjorde hvor mye reduksjon i utslipp ulike tiltak og løsninger kan bidra med. Det inkluderes ...
    • Alternative Rope Materials in Towed Fishing Gear to Reduce Plastic Waste, A Comparative Study of Mechanical Properties and Tolerance Against Wear and Tear 

      Føre, Heidi Moe; Hatlebrekke, Hanne Hjelle; Grimaldo, Eduardo (Chapter; Bokkapittel, 2023-06)
      This paper presents a comparative study assessing the wear tolerance of rope materials in demersal fisheries, specifically seine ropes and dolly ropes. Fourteen different rope materials were assessed in this study, including conventional and alternative commercially available synthetic polymers, and biodegradable materials including natural fibre ropes and custom-made polyester monofilaments. The ...
    • Analysis of bacterial diversity in the intestine of grass carp (Ctenopharyngodon idellus) based on 16S rDNA gene sequences 

      Han, A; Ringø, Einar; Liu, Yuchan; Zhou, Zhigang; He, Suxu; Cao, Yanan; Bin, Yao (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)