• Promiscuous T cell epitopes boosts specific IgM immune response against a P0 peptide antigen from sea lice in different teleost species 

      Leal, Yeny; Velazquez, Janet; Hernandez, Liz; Swain, Jaya Kumari; Rodríguez, Alianet Rodríguez; Martínez, Rebeca; García, Claudia; Ramos, Yassel; Estrada, Mario Pablo; Carpio, Yamila (Journal article; Tidsskriftartikkel, 2019-06-11)
      The development of vaccines employing conserved protein antigens, for instance ribosomal protein P0, has as disadvantage the high degree of identity between pathogen and host proteins due to possible induction of tolerance or auto antibodies in the host organism. To overcome this drawback, peptide-based vaccines have been designed with a proved high efficacy. The use of defined peptides as antigens ...