• Outer Membrane Integrity-Dependent Fluorescence of the Japanese Eel UnaG Protein in Live Escherichia coli Cells 

      Richard, Celine Sarah Marine; Dey, Hymonti; Øyen, Frode Jacobsen; Maqsood, Munazza; Blencke, Hans-Matti (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-07)
      Reporter genes are important tools in many biological disciplines. The discovery of novel reporter genes is relatively rare. However, known reporter genes are constantly applied to novel applications. This study reports the performance of the bilirubin-dependent fluorescent protein UnaG from the Japanese eel Anguilla japonicas in live Escherichia coli cells in response to the disruption of outer ...
    • Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications 

      Dey, Hymonti; Simonovic, Danijela; Hagen, Ingrid Sofie Norberg-Schulz; Vasskog, Terje; Fredheim, Elizabeth G. Aarag; Blencke, Hans-Matti; Anderssen, Trude; Strøm, Morten B.; Haug, Tor (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-10)
      We have synthesised short analogues of the marine antimicrobial peptide Turgencin A from the colonial Arctic ascidian Synoicum turgens. In this study, we focused on a central, cationic 12-residue Cys-Cys loop region within the sequence. Modified (tryptophan- and arginine-enriched) linear peptides were compared with Cys-Cys cyclic derivatives, and both linear and Cys-cyclic peptides were N-terminally ...