Iliev, Dimitar Borisov; Sobhkhez, Mehrdad; Fremmerlid, Kjersti Kongsgården; Jørgensen, Jorunn B (Journal article; Tidsskriftartikkel; Peer reviewed, 2011-10-11)
Background: MyD88 directly interacts and affects IRF activation in mammals, but no information has been available about
lower vertebrates.<p>
<p>Results: Transgenic MyD88 interacts with IRF3 and IRF7A/B and modulates the IRF-induced IFN response and accumulates in
aggresomes in Atlantic salmon.
<p>Conclusion: MyD88 is involved in the regulation of the IRF-induced IFN response in Atlantic ...