Blar i forfatter Artikler, rapporter og annet (Norges fiskerihøgskole) "Cautain, Bastien"

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    • 3-Chloro-N′-(2-hydroxybenzylidene) benzohydrazide: An LSD1-Selective Inhibitor and Iron-Chelating Agent for Anticancer Therapy 

      Sarno, Federica; Papulino, Chiara; Franci, Gianluigi; Andersen, Jeanette hammer; Cautain, Bastien; Melardo, Colombina; Altucci, Lucia; Nebbioso, Angela; Andersen, Jeanette H. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-07)
      Despite the discovery and development of novel therapies, cancer is still a leading cause of death worldwide. In order to grow, tumor cells require large quantities of nutrients involved in metabolic processes, and an increase in iron levels is known to contribute to cancer proliferation. Iron plays an important role in the active site of a number of proteins involved in energy metabolism, DNA ...

    • EU-OPENSCREEN: A novel collaborative approach to facilitate chemical biology 

      Brennecke, Philip; Rasina, Dace; Aubi Catevilla, Oscar; Herzog, Katja; Landskron, Johannes; Cautain, Bastien; Vicente, Francisca; Quintana, Jordi; Mestres, Jordi; Stechmann, Bahne; Ellinger, Bernhard; Brea, Jose; Kolanowski, Jacek L.; Pilarski, Radosław; Orzáez, Mar; Pineda-Lucena, Antonio; Laraia, Luca; Nami, Faranak; Zielenkiewicz, Piotr; Paruch, Kamil; Hansen, Espen; von Kries, Jens P.; Neuenschwander, Martin; Specker, Edgar; Bartunek, Petr; Šímová, Šárka; Leśnikowski, Zbigniew; Krauss, Stefan; Lehtiö, Lari; Bilitewski, Ursula; Brönstrup, Mark; Tasken, Kjetil; Jirgensons, Aigars; Lickert, Heiko; Clausen, Mads H.; Andersen, Jeanette hammer; Vicent, Maria J.; Genilloud, Olga; Martinez, Aurora; Nazaré, Marc; Fecke, Wolfgang; Gribbon, Philip (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-07)
      Compound screening in biological assays and subsequent optimization of hits is indispensable for the development of new molecular research tools and drug candidates. To facilitate such discoveries, the European Research Infrastructure EU-OPENSCREEN was founded recently with the support of its member countries and the European Commission. Its distributed character harnesses complementary knowledge, ...