Blar i forfatter Artikler, rapporter og annet (Norges fiskerihøgskole) "Jenberie, Shiferaw"

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    • The importance of the Atlantic salmon peritoneal cavity B cell response: Local IgM secreting cells are predominant upon Piscirickettsia salmonis infection 

      van der Wal, Yorick Andreas; Jenberie, Shiferaw; Nordli, Henriette; Greiner-Tollersrud, Linn; Kool, Jaap; Jensen, Ingvill; Jørgensen, Jorunn (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-01)
      The intraperitoneal route is favored for administration of inactivated and attenuated vaccines in Atlantic salmon. Nevertheless, the immune responses in the teleost peritoneal cavity (PerC) are still incompletely defined. In this study, we investigated the B cell responses after intraperitoneal Piscirickettsia salmonis (P. salmonis) challenge of Atlantic salmon, focusing on the local PerC response ...

    • Profiling Atlantic salmon B cell populations: CpG-mediated TLR-ligation enhances IgM secretion and modulates immune gene expression 

      Jenberie, Shiferaw; Thim, Hanna Leena; Sunyer, J Oriol; Skjødt, Karsten; Jensen, Ingvill; Jørgensen, Jorunn B (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-02-23)
      While TLR-activated pathways are key regulators of B cell responses in mammals, their impact on teleost B cells are scarcely addressed. Here, the potential of Atlantic salmon B cells to respond to TLR ligands was shown by demonstrating a constitutive expression of nucleic-acid sensing TLRs in magnetic sorted IgM<sup>+</sup> cells. Of the two receptors recognizing CpG in teleosts, <i>tlr9</i> was the ...

    • Salmonid Alphavirus Subtype 3 Induces Prolonged Local B Cell Responses in Atlantic Salmon (Salmo salar) After Intraperitoneal Infection 

      Jenberie, Shiferaw; Penaranda, Ma Michelle Demogina; Thim, Hanna Leena; Styrvold, Morten Bay; Strandskog, Guro; Jørgensen, Jorunn B; Jensen, Ingvill (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-10)
      B cell responses are a crucial part of the adaptive immune response to viral infection. Infection by salmonid alphavirus subtype 3 (SAV3) causes pancreas disease (PD) in Atlantic salmon (<i>Salmo salar</i>) and is a serious concern to the aquaculture industry. In this study, we have used intraperitoneal (IP) infection with SAV3 as a model to characterize local B cell responses in the peritoneal ...