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    • Insight into the mechanism behind oral bioavailability-enhancement by nanosuspensions through combined dissolution/permeation studies 

      Lynnerup, Jakob Tobias; Eriksen, Jonas Borregaard; Bauer-Brandl, Annette; Holsæter, Ann Mari; Brandl, Martin (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-02)
      As numerous new drug candidates are poorly water soluble, enabling formulations are needed to increase their bioavailability for oral administration. Nanoparticles are a conceptually simple, yet resource consuming strategy for increasing drug dissolution rate, as predicting in vivo oral absorption using in vitro dissolution remains difficult. The objective of this study was to obtain insight into ...