• Dominance between plasmids determines the extent of biofilm formation 

      Gama, João Alves; Fredheim, Elizabeth G. Aarag; Cléon, Francois Pierre Alexandre; Reis, Ana Maria; Zilhão, Rita; Dionisio, Francisco (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-26)
      Bacterial biofilms have an impact in medical and industrial environments because they often confer protection to bacteria against harmful agents, and constitute a source from which microorganisms can disperse. Conjugative plasmids can enhance bacterial ability to form biofilms because conjugative pili act as adhesion factors. However, plasmids may interact with each other, either facilitating or ...
    • Interactions between plasmids and other mobile genetic elements affect their transmission and persistence 

      Dionisio, Francisco; Zilhão, Rita; Alves Gama, Joao Pedro (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-14)
      Plasmids are genetic elements that play a role in bacterial evolution by providing new genes that promote adaptation to diverse conditions. Plasmids are also known to reduce bacterial competitiveness in the absence of selection for plasmid-encoded traits. It is easier to understand plasmid persistence when considering the evidence that plasmid maintenance can improve during co-evolution with the ...
    • Plasmid Interactions Can Improve Plasmid Persistence in Bacterial Populations 

      Gama, João Alves; Zilhão, Rita; Dionisio, Francisco (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-31)
      It is difficult to understand plasmid maintenance in the absence of selection and theoretical models predict the conditions for plasmid persistence to be limited. Plasmid-associated fitness costs decrease bacterial competitivity, while imperfect partition allows the emergence of plasmid-free cells during cell division. Although plasmid conjugative transfer allows mobility into plasmid-free cells, ...
    • Plasmid Interactions Can Improve Plasmid Persistence in Bacterial Populations 

      Gama, João Alves; Zilhão, Rita; Dionisio, Francisco (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-31)
      It is difficult to understand plasmid maintenance in the absence of selection and theoretical models predict the conditions for plasmid persistence to be limited. Plasmid-associated fitness costs decrease bacterial competitivity, while imperfect partition allows the emergence of plasmid-free cells during cell division. Although plasmid conjugative transfer allows mobility into plasmid-free cells, ...