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norskArtikler, rapporter og annet (farmasi): Recent submissions
Now showing items 321-340 of 394
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In vitro skin models as a tool in optimization of drug formulation
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-07-30)(Trans)dermal drug therapy is gaining increasing importance in the modern drug development. To fully utilize the potential of this route, it is important to optimize the delivery of active ingredient/drug into/through the skin. The optimal carrier/vehicle can enhance the desired outcome of the therapy therefore the optimization of skin formulations is often included in the early stages of the ... -
The Phospholipid Vesicle-Based Drug Permeability Assay: 5. Development Toward an Automated Procedure for High-Throughput Permeability Screening
(Journal article; Tidsskriftartikkel; Peer reviewed, 2009-02)In-vitro screening for oral absorption has become an essential part of drug discovery and development. Recently, a new phospholipid vesicle-based permeation assay was developed which has shown to satisfyingly predict passive absorption of drugs in humans. The purpose of the current study was to investigate whether the assay may be further developed into a high-throughput tool by automating its ... -
Antibiotic delivery by liposomes from prokaryotic microorganisms: Similia cum similis works better
(Journal article; Tidsskriftartikkel; Preprint; Peer reviewed; Manuskript, 2015-06-25)To date the effectiveness of antibiotics is undermined by microbial resistance, threatening public health worldwide. Enhancing the efficacy of the current antibiotic arsenal is an alternative strategy. The administration of antimicrobials encapsulated in nanocarriers, such as liposomes, is considered a viable option, though with some drawbacks related to limited affinity between conventional liposomes ... -
Resveratrol-loaded liposomes for topical treatment of the vaginal inflammation and infections
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-09-07)Resveratrol (RES), chemically known as 3,5,4′-trihydroxy-trans-stilbene, is a promising multi-targeted antioxidative and anti-inflammatory natural polyphenol. Preclinical studies showed its biological activities against the pathogens of sexually transmitted diseases causing vaginal inflammation and infections. Due to its low solubility and poor bioavailability, the optimal therapeutic uses are ... -
Comorbidities in an asthma population 8-29 years old: a study from the Norwegian Prescription Database
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011-09-23)Purpose: To examine occurrence of chronic diseases and antimicrobial treatment in an asthma population 8-29 years old, compared to the general population. Methods: In this cross-sectional study, the asthma population was identified from the general population (retrieved from a census covering the entire Norwegian population) by using filled prescriptions on asthma drugs as a proxy measure of ... -
Prescribing of drugs for attention-deficit hyperactivity disorder in opioid maintenance treatment patients in Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013-09-27)Background: Attention-deficit hyperactivity disorder (ADHD) is a risk factor for development of substance use disorders. Treatment of ADHD with psychostimulants in patients on opioid maintenance treatment (OMT) has been restricted in Norway. We examined use of prescribed drugs for ADHD in OMT patients, and assessed co-medication with other psychotropics. Methods: Data were drawn from the nationwide ... -
Ny diagnostikk for Alzheimers i Nytt Senter
(Chronicle; Kronikk, 2015-04-23) -
Longitudinal magnetic resonance imaging-based assessment of vascular changes and radiation response in androgen-sensitive prostate carcinoma xenografts under androgen-exposed and androgen-deprived conditions
(Journal article; Tidsskriftartikkel; Peer reviewed, 2010-10)Prostate cancer (PCa) patients receive androgen-deprivation therapy (ADT) to reduce tumor burden. However, complete eradication of PCa is unusual, and recurrent disease is evident within approximately 2 years in high-risk patients. Clinical evidence suggests that combining ADT with radiotherapy improves local control and disease-free survival in these patients compared with radiotherapy alone. ... -
The German ban on GM maize MON810: scientifically justified or unjustified?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2012) -
A pharmacist-led follow-up program for patients with coronary heart disease in North Norway-a qualitative study exploring patient experiences
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014) -
Scientific Opinion on applications (EFSA-GMO-UK-2008-57 and EFSA-GMO-RX-MON15985) for the placing on the market of insect-resistant genetically modified cotton MON 15985 for food and feed uses, import and processing, and for the renewal of authorisation of existing products produced from cotton MON 15985, both under Regulation (EC) No 1829/2003 from Monsanto
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014) -
Statement complementing the EFSA opinion on application EFSA GMO UK 2007 41 (cotton MON 88913 for food and feed uses, import and processing) taking into consideration updated bioinformatic analyses
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014) -
Scientific Opinion on application (EFSA-GMO-NL-2010-77) for the placing on the market of herbicide-tolerant genetically modified cotton GHB614 × LLCotton25 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 from Bayer CropScience
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014) -
Scientific Opinion on the annual post-market environmental monitoring (PMEM) report from Monsanto Europe S.A. on the cultivation of genetically modified maize MON 810 in 2012
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014) -
Mucoadhesive liposomes as new formulation for vaginal delivery of curcumin
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014) -
Development of a biomimetic phospholipid vesicle-based permeation assay for the estimation of intestinal drug permeability
(Journal article; Tidsskriftartikkel, 2014) -
Pax6 regulates the expression of Dkk3 in murine and human cell lines, and altered responses to Wnt signaling are shown in Flpln-3T3 cells stably expressing either the Pax6 or the Pax6(5a) Isoform
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014) -
Determination of the binding mode for the cyclopentapeptide CXCR4 antagonist FC131 using a dual approach of ligand modifications and receptor mutagenesis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014) -
Design, synthesis, and biological evaluation of scaffold-based tripeptidomimetic antagonists for CXC chemokine receptor 4 (CXCR4)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014-07-14) -
Differential in vivo tumorigenicity of distinct subpopulations from a luminal-like breast cancer xenograft
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
