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Prevalence of plasmid-mediated quinolone resistance in Norwegian and Swedish clinical isolates of Escherchia coli and Klebsiella spp.

dc.contributor.advisorSundsfjord, Arnfinn
dc.contributor.advisorSamuelsen, Ørjan
dc.contributor.authorKarah, Nabil
dc.date.accessioned2008-08-25T08:40:49Z
dc.date.available2008-08-25T08:40:49Z
dc.date.issued2008-06-12
dc.description.abstractThe aim of this study was to examine the presence of plasmid-mediated qnr and aac(6')-Ib-cr resistance genes among Escherichia coli and Klebsiella spp. clinical isolates obtained between 2003 and 2005 from Norway and Sweden and showed resistance and/or reduced susceptibility to nalidixic acid and ciprofloxacin, respectively. Prevalence of the qnr (1.6%) and aac(6’)-Ib-cr (14.1%) determinants was low. The qnr-genes were more prevalent in Klebsiella spp. (7.7%) than in E. coli (0.7%). qnrS1 was the most common qnr gene.The qnrS1 genes were located on at least three different plasmid backbones. Nevertheless, the qnrS1-containing area containd matching structures in all the qnrS1-positive isolates.en
dc.format.extent1659496 bytes
dc.format.extent2056 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.identifier.urihttps://hdl.handle.net/10037/1600
dc.identifier.urnURN:NBN:no-uit_munin_1373
dc.language.isoengen
dc.publisherUniversitetet i Tromsøen
dc.publisherUniversity of Tromsøen
dc.rights.accessRightsopenAccess
dc.rights.holderCopyright 2008 The Author(s)
dc.subject.courseIDBIO-3930nor
dc.subjectVDP::Medical disciplines: 700::Basic medical, dental and veterinary science disciplines: 710::Medical microbiology: 715en
dc.subjectEscherchia colien
dc.subjectKlebsiella sppen
dc.subjectqnren
dc.subjectqnrS1en
dc.subjectaac(6')-Ib-cren
dc.subjectplasmid-mediated quinolone resistanceen
dc.titlePrevalence of plasmid-mediated quinolone resistance in Norwegian and Swedish clinical isolates of Escherchia coli and Klebsiella spp.en
dc.typeMaster thesisen
dc.typeMastergradsoppgaveen


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