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dc.contributor.advisorCarlson, Rolf
dc.contributor.authorDescomps, Alexandre Pierre
dc.date.accessioned2008-10-22T06:38:14Z
dc.date.available2008-10-22T06:38:14Z
dc.date.issued2008-06-30
dc.description.abstractThe present work is on the total synthesis of a natural compound found in a mixture of secondary metabolite produced by an alga nearby the cost of Australia. The target molecule, the 4-bromo-3-butyl-5-(dibromomethylene)furan-2(5H)-one, has not previously been proposed. The synthetic route described in this thesis uses cheap and readily available starting materials and the target is reached after six synthetic steps. Several new results have been obtained: selective monolithiation of a dibromofuran; Suzuki coupling with butyl boronic acid; a regioselective photo-oxidation of furan. The final step of the synthesis, a dibromoolefination, has not yet been accomplished.en
dc.format.extent12008526 bytes
dc.format.extent2075 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.identifier.urihttps://hdl.handle.net/10037/1641
dc.identifier.urnURN:NBN:no-uit_munin_1410
dc.language.isoengen
dc.publisherUniversitetet i Tromsøen
dc.publisherUniversity of Tromsøen
dc.rights.accessRightsopenAccess
dc.rights.holderCopyright 2008 The Author(s)
dc.subject.courseIDKJE-3900nor
dc.subjectVDP::Mathematics and natural science: 400::Chemistry: 440::Organic chemistry: 441en
dc.subjectsinglet oxygenen
dc.subjectSuzuki couplingen
dc.subjecthalogen-metal exchangeen
dc.subjectwittig reactionen
dc.subjecttotal synthesisen
dc.subjectretro-analysisen
dc.subjectalkylation of furanen
dc.subjectregioisomereen
dc.subjectmono lithiationen
dc.subjectfimbrolideen
dc.titleOn the synthesis of a fimbrolideen
dc.typeMaster thesisen
dc.typeMastergradsoppgaveen


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