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dc.contributor.authorSchots, Pauke C.
dc.contributor.authorPedersen, Alice Marie
dc.contributor.authorEilertsen, Karl-Erik
dc.contributor.authorOlsen, Ragnar Ludvig
dc.contributor.authorLarsen, Terje
dc.date.accessioned2020-06-30T07:11:21Z
dc.date.available2020-06-30T07:11:21Z
dc.date.issued2020-06-26
dc.description.abstractThe consumption of seafood and the use of fish oil for the production of nutraceuticals and fish feed have increased over the past decades due the high content of long-chain polyunsaturated omega-3 fatty acids. This increase has put pressure on the sustainability of fisheries. One way to overcome the limited supply of fish oil is to harvest lower in the marine food web. <i>Calanus finmarchicus</i>, feeding on phytoplankton, is a small copepod constituting a considerable biomass in the North Atlantic and is a novel source of omega-3 fatty acids. The oil is, however, different from other commercial marine oils in terms of chemistry and, possibly, bioactivity since it contains wax esters. Wax esters are fatty acids that are esterified with alcohols. In addition to the long-chain polyunsaturated omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), the oil is also rich in stearidonic acid (SDA), long-chain monounsaturated fatty acids, and the long-chain fatty alcohols eicosenol and docosenol. Recent animal studies have indicated anti-inflammatory and anti-obesogenic actions of this copepod oil beyond that provided by EPA and DHA. This review will discuss potential mechanisms behind these beneficial effects of the oil, focusing on the impact of the various components of the oil. The health effects of EPA and DHA are well recognized, whereas long-chain monounsaturated fatty acids and long-chain fatty alcohols have to a large degree been overlooked in relation to human health. Recently, however the fatty alcohols have received interest as potential targets for improved health <i>via</i> conversion to their corresponding fatty acids. Together, the different lipid components of the oil from <i>C. finmarchicus</i> may have potential as nutraceuticals for reducing obesity and obesity-related metabolic disorders.en_US
dc.identifier.citationSchots PC, Pedersen AM, Eilertsen KE, Olsen RL, Larsen t. Possible Health Effects of a Wax Ester Rich Marine Oil. Frontiers in Pharmacology. 2020en_US
dc.identifier.cristinIDFRIDAID 1817666
dc.identifier.doihttps://doi.org/10.3389/fphar.2020.00961
dc.identifier.issn1663-9812
dc.identifier.urihttps://hdl.handle.net/10037/18699
dc.language.isoengen_US
dc.publisherFrontiers Mediaen_US
dc.relation.journalFrontiers in Pharmacology
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2020 The Author(s)en_US
dc.subjectVDP::Medical disciplines: 700en_US
dc.subjectVDP::Medisinske Fag: 700en_US
dc.titlePossible Health Effects of a Wax Ester Rich Marine Oilen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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