Blar i forfatter Mastergradsoppgaver i farmasi "Brurok, Sunniva"
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High throughput lipolysis-permeation in vitro model employing the mucus-PVPA barriers to assess drug absorption from lipid-based delivery systems
Brurok, Sunniva (Mastergradsoppgave; Master thesis, 2020-05-14)In vitro lipolysis models are commonly used to assess the performance of lipid-based drug delivery systems (LbDDSs) in terms of their drug absorption potential; however, this in vitro approach has not always shown to correlate well with in vivo data. Several studies suggest that adding an absorption step to the in vitro lipolysis model would give a better estimation of absorption for drugs incorporated ...