Blar i forfatter Mastergradsoppgaver i farmasi "Chemeda, Ayantu Edossa"
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Topical liposomes treated by probe-sonication. Study on process and composition using statistical experimental design and multivariate evaluation
Chemeda, Ayantu Edossa (Master thesis; Mastergradsoppgave, 2015-10-01)Abstract A size distribution between 200 and 300 nm and a high drug entrapment is desirable for liposomes intended for topical application. In an early phase of drug development, small batch sizes are also wanted. Dual Asymmetric Centrifugation (DAC) meets these requirement and was our method of choice. But, after successful production of a few DAC-liposome batches with drug entrapment of ...