Blar i forfatter Mastergradsoppgaver i farmasi "Fedreheim, Elena"
-
Development of an in vitro model to study compromised skin: pigskin versus the Phospholipid Vesicle-based Permeation Assay
Fedreheim, Elena (Master thesis; Mastergradsoppgave, 2013-05-20)When the skin barrier is reduced, penetration of topical and transdermal drugs could potentially be enhanced and the risk of systemic effects is increased. The studies analysing penetration through intact or diseased skin are often limited by the variability in obtaining specimens of representative skin. The phospholipid vesicle-based permeation assay is an artificial barrier mimicking human stratum ...