Blar i forfatter Mastergradsoppgaver i farmasi "Milicevic, Dusan"
-
Modelling of serotonergic receptors and molecular optimization of X-ray crystal structures of serotonin transporter and their interactions with exogenous compounds
Milicevic, Dusan (Master thesis; Mastergradsoppgave, 2016-05-12)The serotonin (5-hydroxytryptamine, 5-HT) receptors and transporter are in the serotonergic neurotransmission system, and believed to have a major role in pathology of depression. They are of pharmacological importance, being targeted by many nowadays antidepressants. It is therefore of great interest to understand their structural and functional properties for development of future drugs. There ...