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dc.contributor.authorJohansson, Jonas
dc.contributor.authorStrand, Bjørn Heine
dc.contributor.authorMorseth, Bente
dc.contributor.authorHopstock, Laila Arnesdatter
dc.contributor.authorGrimsgaard, Sameline
dc.date.accessioned2020-11-20T13:07:31Z
dc.date.available2020-11-20T13:07:31Z
dc.date.issued2020-11-10
dc.description.abstract<p><i>Background - </i>The European Working Group on Sarcopenia in Older People (EWGSOP2) recommends grip strength and chair stand tests to be used as primary defining measures. It is unclear how either test affects prevalence estimates. <p><i>Methods - </i>This cross-sectional study involved 3498 community-dwelling participants (40–84 years) from the 7th Tromsø Study survey (2015–2016). We used grip strength, five-repetition chair stands, four-meter Walk Speed Test, Timed-Up-and-Go (TUG) and Dual-Energy X-ray Absorptiometry measurements. Data were analyzed using multiple linear regression models and ROC-curves. <p><i>Results - </i>Probable and confirmed sarcopenia prevalence was 1.3 and 4.4% based on grip strength and chair stands, respectively. There was very low agreement between grip strength and chair stand cut-offs (κ = 0.07), with only 4.3% of participants defined as having probable sarcopenia overlapping in the two criteria. Participants with grip strength-based sarcopenia had lower mean height, weight, waist circumference, and appendicular lean mass relative to body height (ALM<sub>height</sub><sup>2</sup>) than non-sarcopenic participants (all p < 0.001), after adjusting for multiple covariates. Conversely, participants with chair stand-based sarcopenia had similar height, higher weight, waist circumference and body fat% compared to non-sarcopenic participants (all p < 0.05). Area-under-curves (AUCs) for TUG-time were significantly larger when using chair stand instead of grip strength cut-offs (0.86, 95% CI 0.84–0.89 vs. 0.75, 95% CI 0.69–0.83). <p><i>Conclusions - </i>Using chair stands instead of grip strength more than doubled probable sarcopenia prevalence across all ages. The two measures defined individuals of contradictory anthropometrics, body composition, and dissimilar physical function to have probable sarcopenia. Researchers should further evaluate the consequences of using different strength measures in the EWGSOP2 definition to classify sarcopenia.en_US
dc.identifier.citationJohansson J, Strand BH, Morseth B, Hopstock LA, Grimsgaard sg. Differences in sarcopenia prevalence between upper-body and lower-body based EWGSOP2 muscle strength criteria: the Tromsø study 2015–2016. BMC Geriatrics. 2020;20(461)en_US
dc.identifier.cristinIDFRIDAID 1846475
dc.identifier.doi10.1186/s12877-020-01860-w
dc.identifier.issn1471-2318
dc.identifier.urihttps://hdl.handle.net/10037/19890
dc.language.isoengen_US
dc.publisherBMCen_US
dc.relation.journalBMC Geriatrics
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2020 The Author(s)en_US
dc.subjectVDP::Medical disciplines: 700::Clinical medical disciplines: 750::Geriatrics: 778en_US
dc.subjectVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Geriatri: 778en_US
dc.titleDifferences in sarcopenia prevalence between upper-body and lower-body based EWGSOP2 muscle strength criteria: the Tromsø study 2015–2016en_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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