Patient selection for islet or solid organ pancreas transplantation: experiences from a multidisciplinary outpatient-clinic approach
Permanent lenke
https://hdl.handle.net/10037/21724Dato
2021-02Type
Journal articleTidsskriftartikkel
Peer reviewed
Forfatter
Nordheim, Espen; Lindahl, Jørn Petter Hanto; Carlsen, Rasmus Kirkeskov; Åsberg, Anders; Birkeland, Kåre I.; Horneland, Rune; Boye, Birgitte; Scholz, Hanne; Jenssen, Trond GeirSammendrag
Research design and methods - Medical charts of all patients evaluated for βCRT between 2010 and 2020 in Norway were retrospectively analysed and the outcome of patients receiving βCRT were studied.
Results - One hundred and forty-four patients were assessed for βCRT eligibility between 2010 and 2020. After MDT evaluation was introduced for βCRT eligibility in 2015, the percentage of referred patients accepted for the transplant waiting list fell from 84% to 40% (P < 0.005). One year after transplantation, 73% of the PTA and none of the ITX patients were independent of exogenous insulin, 8% of the PTA and 90% of the ITX patients had partial graft function while 19% of the PTA and 10% of the ITX patients suffered from graft loss.
Conclusion - The acceptance rate for βCRT was significantly reduced during a 10-year observation period and 81% of the PTA and 90% of the ITX patients had partial or normal graft function 1 year post-transplant.