Two-year motor outcomes associated with the dose of NICU based physical therapy: The Noppi RCT
AuthorØberg, Gunn Kristin; Handegård, Bjørn Helge; Campbell, Suzann K.; Ustad, Tordis; Fjørtoft, Toril Larsson; Kaaresen, Per Ivar; Girolami, Gay L.
Aims - To examine the effect on motor performance at 24-months corrected age following a parent-administered intervention performed with infants born preterm in the NICU. Intervention dosing and longitudinal motor performance were also analyzed.
Study design - Single-blinded randomized multicenter clinical trial.
Subjects - 153 infants born, gestational age ≤ 32 weeks at birth, were randomized into intervention or control group.
Outcome measures - Infant Motor Performance Screening Test, Test of Infant Motor Performance, Peabody Developmental Motor Scales-2.
Results - No significant difference was found between the intervention and the control group assessed with the PDMS-2 at 24-months CA. However, a significant positive association was found between dosing and the Gross Motor and Total Motor PDMS-2 scores. Analysis of longitudinal motor performance showed a decreasing motor performance between 6- and 24-months corrected age in both groups.
Conclusions - There was no difference in motor performance between groups at 24-months corrected age. However, increased intervention dosage was positively associated with improved motor outcome.