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dc.contributor.authorAnke, Pablo
dc.contributor.authorPedersen, Lars Kjelsberg
dc.contributor.authorMathiesen, Ellisiv Bøgeberg
dc.contributor.authorIngebrigtsen, Tor
dc.date.accessioned2023-01-12T09:19:55Z
dc.date.available2023-01-12T09:19:55Z
dc.date.issued2022-10-14
dc.description.abstractObjective: We analyzed data from the Norwegian Stroke Registry (NSR) to study access to and outcomes of decompressive hemicraniectomy for brain infarction in a nationwide routine clinical setting. We also discretionary assessed whether the outcomes were comparable with those achieved in randomized controlled trials (RCTs), and whether the use was in accordance with guidelines. Methods: The NSR is a nationwide (population 5.3 million) clinical quality registry. We included all stroke-cases operated in 2017 through 2019, and retrieved data on baseline characteristics, treatment and functional outcome after three months (dichotomized modified Rankin Scale score; favorable (0-3) or unfavorable (4-6)). Crude treatment rates and the expected proportion of patients transferred from a local hospital to a stroke-center for the operation were estimated, based on the total population’s distribution of residency. Results: The 68 cases were 17 (25%) women and 51 (75%) men with a median National Institute of Health Stroke Scale (NIHSS) score on admission of 14.0 (inter-quartile range (IQR) 11.0) and a median time from onset to hemicraniectomy of 34.3 (IQR 40.9) hours. The crude treatment rate varied between regions from 0.29 to 1.40 operations per 100,000 population per year, and the proportion transferred from a local hospital (50%) was lower than expected (68%). A favorable outcome was achieved in 20/52 (38.5%) cases. Conclusions: The findings indicate gender- and geographic-inequalities in access. Among operated cases, outcomes were comparable with those reported from RCTs, and the use in accordance with recommendations in the current guidelines from the American Stroke Association.en_US
dc.identifier.citationAnke, Pedersen, Mathiesen, Ingebrigtsen. Decompressive hemicraniectomy for space-occupying brain infarction: Nationwide population-based registry study. Journal of Stroke & Cerebrovascular Diseases. 2022;31:1-4en_US
dc.identifier.cristinIDFRIDAID 2101807
dc.identifier.doi10.1016/j.jstrokecerebrovasdis.2022.106831
dc.identifier.issn1052-3057
dc.identifier.issn1532-8511
dc.identifier.urihttps://hdl.handle.net/10037/28178
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.relation.journalJournal of Stroke & Cerebrovascular Diseases
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2022 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.rightsAttribution 4.0 International (CC BY 4.0)en_US
dc.subject.hrcsNevrologisk: Kirurgi
dc.subject.hrcsNeurological : Surgery
dc.subjectVDP::Medisinske fag: 700::Klinisk medisinske fag: 750::Nevrokirurgi: 786en_US
dc.subjectVDP::Midical sciences: 700::Clinical medical sciences: 750::Neurosurgery: 786en_US
dc.subjectVDP::Medisinske fag: 700::Klinisk medisinske fag: 750::Nevrologi: 752en_US
dc.subjectVDP::Midical sciences: 700::Clinical medical sciences: 750::Neurology: 752en_US
dc.subjectDekompresjon, kirurgisk / Decompression, Surgicalen_US
dc.subjectHjerneslag / Cerebral strokeen_US
dc.subjectKvalitetsregister / Quality registeren_US
dc.titleDecompressive hemicraniectomy for space-occupying brain infarction: Nationwide population-based registry studyen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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Attribution 4.0 International (CC BY 4.0)
Med mindre det står noe annet, er denne innførselens lisens beskrevet som Attribution 4.0 International (CC BY 4.0)