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dc.contributor.authorNieder, Carsten
dc.contributor.authorStanisavljevic, Luka
dc.contributor.authorMannsåker, Bård
dc.contributor.authorHaukland, Ellinor Christin
dc.date.accessioned2023-06-27T07:09:41Z
dc.date.available2023-06-27T07:09:41Z
dc.date.issued2023-04-03
dc.description.abstractBackground This study analyzed mortality after radiotherapy for bone metastases (287 courses). Endpoints such as treatment in the last month of life and death within 30, 35 and 40 days from start of radiotherapy were evaluated.<p> <p>Methods Different baseline parameters including but not limited to blood test results and patterns of metastases were assessed for association with early death. After univariate analyses, multi-nominal logistic regression was employed. <p>Results Of 287 treatment courses, 42 (15%) took place in the last month of life. Mortality from start of radiotherapy was 13% (30-day), 15% (35-day) and 18% (40-day), respectively. We identified three significant predictors of 30-day mortality (performance status (≤50, 60–70, 80–100), weight loss of at least 10% within 6 months (yes/no), pleural effusion (present/absent)) and employed these to construct a predictive model with 5 strata and mortality rates of 0–75%. All predictors of 30-day mortality were also associated with both, 35- and 40-day mortality. <p>Conclusion Early death was not limited to the first 30 days after start of radiotherapy. For different cut-of points, similar predictive factors emerged. A model based on three robust predictors was developed.en_US
dc.identifier.citationNieder, Stanisavljevic, Mannsåker, Haukland. Early death after palliative radiation treatment: 30-, 35- and 40-day mortality data and statistically robust predictors. Radiation Oncology. 2023;18(1):59en_US
dc.identifier.cristinIDFRIDAID 2142226
dc.identifier.doi10.1186/s13014-023-02253-0
dc.identifier.issn1748-717X
dc.identifier.urihttps://hdl.handle.net/10037/29501
dc.language.isoengen_US
dc.publisherBMCen_US
dc.relation.journalRadiation Oncology
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2023 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.rightsAttribution 4.0 International (CC BY 4.0)en_US
dc.titleEarly death after palliative radiation treatment: 30-, 35- and 40-day mortality data and statistically robust predictorsen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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Attribution 4.0 International (CC BY 4.0)
Med mindre det står noe annet, er denne innførselens lisens beskrevet som Attribution 4.0 International (CC BY 4.0)