Institutt for klinisk medisin: Recent submissions

Now showing items 441-460 of 1930

    • Parents’ perspectives on preparing for parenthood: a qualitative study on Greenland’s universal parenting programme MANU 0–1 year 

      Ingemann, Christine; Jensen, Else; Olesen, Ingelise; Tjørnhøj-Thomsen, Tine; Kvernmo, Siv; Larsen, Christina Viskum Lytken (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-20)
      <p><b> Background</b> The transition to parenthood has received increasing attention in research, partly due to evidence pointing out the crucial developmental period of a child’s first thousand days. Parenting programmes aim to prepare and support families in their transition and distress. For a programme to be implemented successfully it is important to consider parents’ needs and resources. ...

    • Genetically predicted cortisol levels and risk of venous thromboembolism 

      Allarai, Elias; Lee, Wei-Hsuan; Burgess, Stephen; Larsson, Susanna C.; Lindstrom, Sara; Wang, Lu; Smith, Erin N.; Gordon, William; Van Hylckama Vlieg, Astrid; De Andrade, Mariza; Brody, Jennifer A.; Pattee, Jack W.; Haessler, Jeffrey; Brumpton, Ben Michael; Chasman, Daniel I.; Suchon, Pierre; Chen, Ming-Huei; Turman, Constance; Germain, Marine; Wiggins, Kerri L.; Macdonald, James; Brækkan, Sigrid Kufaas; Armasu, Sebastian M.; Pankratz, Nathan; Jackson, Rabecca D.; Nielsen, Jonas B; Giulianini, Franco; Puurunen, Marja K.; Ibrahim, Manal; Heckbert, Susan R.; Bammler, Theo K.; Frazer, Kelly A.; Mccauley, Bryan M.; Taylor, Kent; Pankow, James S.; Reiner, Alexander P.; Gabrielsen, Maiken Elvestad; Deleuze, Jean-Francois; O'Donnell, Chris J.; Kim, Jihye; Mcknight, Barbara; Kraft, Peter; Hansen, John Bjarne; Rosendaal, Frits Richard; Heit, John A.; Psaty, Bruce M.; Tang, Weihong; Kooperberg, Charles; Hveem, Kristian; Ridker, Paul M.; Morange, Pierre-Emmanuel; Johnson, Andrew D.; Kabrhel, Christopher; Alexandretrégouët, David; Smith, Nicholas L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-19)
      Introduction - In observational studies, venous thromboembolism (VTE) has been associated with Cushing’s syndrome and with persistent mental stress, two conditions associated with higher cortisol levels. However, it remains unknown whether high cortisol levels within the usual range are causally associated with VTE risk. We aimed to assess the association between plasma cortisol levels and VTE risk ...

    • The development of a tool to assess medical students’ non-technical skills–The Norwegian medical students’ non-technical skills (NorMS-NTS) 

      Prydz, Katrine; Dieckmann, Gerhard Peter; Musson, David; Wisborg, Torben (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-07)
      Purpose - New physicians need to master non-technical skills (NTS), as high levels of NTS have been shown to increase patient safety. It has also been shown that NTS can be improved through training. This study aimed to establish the necessary NTS for Norwegian medical students to create a tool for formative and summative assessments.<p> <p>Methods - Focus group interviews were conducted with ...

    • Associations of serum 25-hydroxyvitamin D and subjective sleep measures in an arctic population: Insights from the population-based Tromsø Study 

      Uhlving Larsen, Anette; Hopstock, Laila Arnesdatter; Jorde, Rolf; Grimnes, Guri (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-06)
      Objective - To investigate the relation between serum 25-hydroxyvitamin D (s-25(OH)D) and subjective sleep measures in an Arctic population (69°N).<p> <p>Methods - Cross-sectional data was collected from 21,083 individuals (aged ≥40 years) participating in the population based Tromsø Study: Tromsø7 (2015–2016). The present study included 20,438 participants, after having excluded respondents ...

    • The precarity of patient participation - a qualitative interview study of experiences from the acute stroke and rehabilitation journey 

      Sivertsen, Marianne; De Jaegher, Hanne; Alstadhaug, Karl Bjørnar; Arntzen, Ellen Christin; Normann, Britt (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-07)
      Introduction: Active patient participation is an important factor in optimizing post-stroke recovery, yet it is often low, regardless of stroke severity. The reasons behind this trend are unclear.<p> <p>Purpose: To explore how people who have suffered a stroke, perceive the transition from independence to dependence and whether their role in post-stroke rehabilitation influences active ...

    • Sex Differences in Age-Related Loss of Kidney Function 

      Melsom, Toralf; Norvik, Jon Viljar; Enoksen, Inger Therese; Stefansson, Vidar Tor Nyborg; Mathisen, Ulla Dorte; Fuskevåg, Ole Martin; Jenssen, Trond Geir; Solbu, Marit Dahl; Eriksen, Bjørn Odvar (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-30)
      Background - CKD is more prevalent in women, but more men receive kidney replacement therapy for kidney failure. This apparent contradiction is not well understood.<p> <p>Methods - We investigated sex differences in the loss of kidney function and whether any sex disparities could be explained by comorbidity or CKD risk factors. In the Renal Iohexol Clearance Survey (RENIS) in northern Europe, ...

    • Meticillinresistente gule stafylokokker i sårsekret hos barn 

      Thaulow, Christian Magnus; Lindemann, Paul Christoffer; Klingenberg, Claus Andreas (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-07)
      BAKGRUNN - Hud- og bløtvevsinfeksjoner er vanlig hos barn. Vi ønsket å undersøke forekomsten av meticillinresistens blant gule stafylokokker i sårsekret fra barn i Norge.<p> <p>MATERIALE OG METODE - Vi gjennomførte en observasjonsstudie basert på data fra Norsk overvåkingssystem for antibiotikaresistens hos mikrober (NORM) for perioden 2013–21. Resistensdata fra sårsekret med vekst av gule ...

    • Amoxicillin did not Reduce Modic Change Oedema in Patients with Chronic Low Back pain - subgroup Analyses of a Randomised Trial (the AIM study) 

      Kristoffersen, Per Martin; Vetti, Nils; Grøvle, Lars; Brox, Jens Ivar; Bråten, Lars Christian Haugli; Grotle, Margreth; Haugen, Anne Julsrud; Rolfsen, Mads Peder; Froholdt, Anne; Skouen, Jan Sture; Lutro, Olav; Marchand, Gunn Hege; Anke, Audny Gabriele Wagner; Zwart, John Anker Henrik; Storheim, Kjersti; Assmus, Jörg; Espeland, Ansgar (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-12)
      <p><b> Study Design. </b> Exploratory subgroup analyses of a randomised trial (Antibiotics In Modic changes (AIM) study). <p><b> Objective. </b> To assess the effect of amoxicillin versus placebo in reducing Modic change (MC) oedema in patients with chronic low back pain (LBP). <p><b> Summary of Background Data. </b> The AIM study showed a small, clinically insignificant effect of ...

    • European recommendations on practices in pediatric neuroradiology: consensus document from the European Society of Neuroradiology (ESNR), European Society of Paediatric Radiology (ESPR) and European Union of Medical Specialists Division of Neuroradiology (UEMS) 

      Rossi, Andrea; Argyropoulou, Maria; Zlatareva, Dora; Boulouis, Gregoire; Pizzini, Francesca B.; van den Hauwe, Luc; Raissaki, Maria; Pruvo, Jean-Pierre; Rosendahl, Karen; Hoffmann, Chen; Sundgren, Pia C.; Mankad, Kshitij; Severino, Mariasavina; Adamsbaum, Catherine; Altmann-Schneider, Irmhild; Chateil, Jean-François; Connolly, Daniel J.; Dangouloff-Ros, Volodia; D’Arco, Felice; Donoghue, Veronica; Girard, Nadine; Krystal, Sidney; Lequin, Maarten Hans; Narayana, Dhananjaya; Porto, Luciana; Vasquez, Elida; Xydis, Vasileios (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-05)
      Pediatric neuroradiology is a subspecialty within radiology, with possible pathways to train within the discipline from neuroradiology or pediatric radiology. Formalized pediatric neuroradiology training programs are not available in most European countries. We aimed to construct a European consensus document providing recommendations for the safe practice of pediatric neuroradiology. We particularly ...

    • Using automated syllable counting to detect missing information in speech transcripts from clinical settings 

      Diaz-Asper, Marama; Holmlund, Terje Bektesevic; Chandler, Chelsea; Diaz-Asper, Catherine; Foltz, Peter W.; Cohen, Alex S.; Elvevåg, Brita (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-05)
      Speech rate and quantity reflect clinical state; thus automated transcription holds potential clinical applications. We describe two datasets where recording quality and speaker characteristics affected transcription accuracy. Transcripts of low-quality recordings omitted significant portions of speech. An automated syllable counter estimated actual speech output and quantified the amount of ...

    • Early empirical antibiotics and adverse clinical outcomes in infants born very preterm: A population-based cohort 

      Vatne, Anlaug; Hapnes, Nina; Stensvold, Hans Jørgen; Dalen, Ingvild; Guthe, Hans Jørgen Timm; Støen, Ragnhild; Brigtsen, Anne Karin; Rønnestad, Arild Erland; Klingenberg, Claus Andreas (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-28)
      Objective The objective of this study was to evaluate the association between empirical antibiotic therapy in the first postnatal week in uninfected infants born very preterm and the risk of adverse outcomes until discharge.<p> <p>Study design Population-based, nationwide registry study in Norway including all live-born infants with a gestational age <32 weeks surviving first postnatal week without ...

    • Translating Natural Language Processing into Mainstream Schizophrenia Assessment 

      Elvevåg, Brita; Cohen, Alex S. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-01)
      Natural language processing (NLP) is a multidisciplinary field that involves objectifying aspects of language. Specifically, it understands human language by leveraging statistical and linguistic knowledge. NLP’s potential for enhancing the administration, accuracy, and objectivity of clinical assessments in psychiatry has been touted, as well as its potential for promoting equity in health care. ...

    • Høyt nivå av tungmetaller i krabbe 

      Averina, Maria; Monsen, Anne-Lise Bjørke; Bolann, Bjørn Johan; Brox, Jan; Eggesbø, Merete; Hokstad, Ingrid; Huber, Sandra; Ørebech, Peter Th (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-01)
      Krabber er populær sjømat, men kan inneholde til dels store mengder miljøgifter. Innholdet er mange steder i Norge så høyt at inntak av brunmaten generelt bør frarådes.

    • Laktat i fosterskalpblodprøve som markør for føtal hypoksi 

      Fosse, Gunhild Øygard; Averina, Maria (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-11)
      Evidensgrunnlaget for å ta blodprøver fra fosterskalpen er svakt. Fører prøvene til færre intervensjoner eller bedre utfall for fosteret?

    • Hvordan forbedre? 

      Joakimsen, Peder (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-13)
      Hei, det er vanskelig ut fra innlegget å se hva som faktisk skal kunne bidra til en «bredere rekrutteringsbase»

    • En mann i 40-årene med akutt forvirring 

      Karlberg, Merethe; Thoresen, Hanne; Berg, Diana Hristova; Ciopat, Oana-Gratiela; Alstadhaug, Karl Bjørnar (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-07)
      Rask og adekvat utredning av akutte nevropsykiatriske symptomer er avgjørende for effektiv behandling. Her beskriver vi en pasient med en karakteristisk, men relativt sjelden sykdom.

    • Public and outpatients’ awareness of calling emergency medical services immediately by acute stroke in an upper middle-income country: a cross-sectional questionnaire study in greater Gaborone, Botswana 

      Ookeditse, Ookeditse; Ookeditse, Kebadiretse K.; Motswakadikgwa, Thusego R.; Masilo, Gosiame; Bogatsu, Yaone; Lekobe, Baleufi Calstro; Mosepele, Mosepele; Schirmer, Henrik; Johnsen, Stein Harald (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-14)
      Objectives - In this cross-sectional study from Botswana, we investigated awareness of calling emergency medical services (EMS) and seeking immediate medical assistance by acute stroke among stroke risk outpatients and public.<p> <p>Method - Closed-ended questionnaires on awareness of calling EMS and seeking immediate medical assistance by acute stroke, were administered by research assistants ...

    • Transitioning patients with juvenile idiopathic arthritis to adult care: the Nordic experience 

      Mikola, Katriina; Rebane, Katariina; Arnstad, Ellen Dalen; Berntson, Lillemor; Fasth, Anders; Glerup, Mia; Herlin, Troels; Kautiainen, Hannu; Nielsen, Susan; Nordal, Ellen Berit; Peltoniemi, Suvi; Rygg, Marite; Rypdal, Veronika; Zak, Marek; Aalto, Kristiina (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-01)
      Background: With juvenile idiopathic arthritis (JIA), there are several protocols and practices used worldwide for the transition from paediatric to adult care. In this study, we examined the transferral rates and disease activity after transition, as well as the disease- and health-related outcomes. We also introduce the transition practices employed in the Nordic countries.<p> <p>Methods: The ...

    • Early surfactant and non-invasive ventilation versus intubation and surfactant: a propensity score-matched national study 

      Reigstad, Hallvard; Hufthammer, Karl Ove; Rønnestad, Arild Erland; Klingenberg, Claus Andreas; Stensvold, Hans Jørgen; Markestad, Trond Jacob (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-27)
      <p><b> Objective</b> To compare outcome after less invasive surfactant administration (LISA) and primary endotracheal intubation (non-LISA) in infants born before gestational age (GA) 28 weeks. <p><b> Setting</b> All neonatal intensive care units (NICUs) in Norway during 2012–2018. <p><b> Methods</b> Defined population-based data were prospectively entered into a national registry. We ...

    • A four-month home-based tDCS study on patients with Alzheimer’s disease 

      Grønli, Ole Kristian; Rasmussen, Ingrid Daae; Aslaksen, Per M; Bystad, Martin Kragnes (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-19)
      In the present open-label study, our first aim was to study the tolerability and feasibility of long-term treatment with transcranial direct current stimulation (tDCS) and the second aim was to measure whether the treatment led to cognitive improvement. Participants with AD used a tDCS home-treatment kit inducing a low current (2 mA) via two scalp electrodes 30 minutes daily for 4 months. A total ...