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dc.contributor.authorPitron, Victor
dc.contributor.authorKöteles, Ferenc Gabor
dc.contributor.authorNordin, Steven
dc.contributor.authorHaanes, Jan Vilis
dc.contributor.authorHillert, Lena
dc.contributor.authorLéger, Damien
dc.contributor.authorLemogne, Cédric
dc.contributor.authorSzemerszky, Renata
dc.contributor.authorvan Kamp, Irene
dc.contributor.authorvan Thriel, Christoph
dc.contributor.authorWitthöft, Michael
dc.contributor.authorVan den Bergh, Omer
dc.date.accessioned2024-02-19T09:51:50Z
dc.date.available2024-02-19T09:51:50Z
dc.date.issued2023-12-27
dc.description.abstractThe recent review of Molot et al. (2023) appropriately emphasizes Multiple Chemical Sensitivity (MCS) as a growing health issue and the necessity of dedicated healthcare and medical education. The authors explain MCS mainly as the result of the sensitization of transient receptor potential (TRP) receptors, notably TRPV1 and TRPA1, and oppose this explanation to psychological processes as a causal explanation. We argue that: 1. critical evidence from double-blind exposure studies showing patients’ inability to discriminate between actual and sham exposure questions this claim; 2. the interpretation of the role of TRP-receptors fails to appreciate the importance of chemicals as stressors for MCS patients and may confound cause and effect; 3. the evidence supporting a causal role of psychological processes is largely neglected; 4. the opposition between biological and psychological causes is not helpful in trying to understand MCS. Most importantly, treatment suggestions based only on the hypothetical role of TRP-receptors may aggravate the burden of MCS on both patients and society.en_US
dc.identifier.citationPitron, Köteles, Nordin, Haanes, Hillert, Léger, Lemogne, Szemerszky, van Kamp, van Thriel, Witthöft, Van den Bergh. Multiple Chemical Sensitivity: Catching up to what kind of science?. Neuroscience and Biobehavioral Reviews. 2023en_US
dc.identifier.cristinIDFRIDAID 2217801
dc.identifier.doi10.1016/j.neubiorev.2023.105524
dc.identifier.issn0149-7634
dc.identifier.issn1873-7528
dc.identifier.urihttps://hdl.handle.net/10037/32966
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.relation.journalNeuroscience and Biobehavioral Reviews
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2023 The Author(s)en_US
dc.titleMultiple Chemical Sensitivity: Catching up to what kind of science?en_US
dc.type.versionacceptedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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