dc.contributor.author | Eilertsen, Trond | |
dc.contributor.author | Kvammen, Bjørn Øivind | |
dc.contributor.author | Grimstad, Øystein | |
dc.date.accessioned | 2024-10-01T11:26:19Z | |
dc.date.available | 2024-10-01T11:26:19Z | |
dc.date.issued | 2024-03-01 | |
dc.description.abstract | Introduction - Hyperhidrosis is characterized by unpredictable, uncontrollable and excessive sweating. It occurs at rest and is not related to temperature. Hyperhidrosis is a common disorder that has a negative impact on quality of life (QoL). The aim of this quality assurance study was to investigate how treatment of palmoplantar hyperhidrosis with botulinum toxin A (BTX-A) and botulinum toxin B (BTX-B) led to improvement of patient reported outcome measures related to QoL.<p>
<p>Methods - A total of 35 patients with palmar and/or plantar hyperhidrosis who had received BTX-A (Dysport®) and BTX-B (NeuroBloc®) for palmar hyperhidrosis and BTX-B for plantar hyperhidrosis were included in this study. In total, palms were injected with a median dose (low to high) of 400 (100–550) units BTX-A and a median dose (low to high) of 200 (200–500) units. BTX-B was used in the thenar and hypothenar areas to avoid muscle weakness. In the soles a total median dose (low to high) of 600 (475–1000) units BTX-B was injected.<p>
<p>Results - At follow-up 2 weeks post-treatment, patients’ Dermatology Life Quality Index (DLQI) score improved from 13 to 2 (p < 0.001).<p>
<p>Conclusion - We found that BTX-A and BTX-B treatment for palmar hyperhidrosis and BTX-B treatment for plantar hyperhidrosis led to a substantial improvement of QoL. | en_US |
dc.identifier.citation | Eilertsen, Kvammen B, Grimstad. Botulinum Toxin A and B for Palmoplantar Hyperhidrosis. Dermatologic Therapy. 2024;14:805-811 | |
dc.identifier.cristinID | FRIDAID 2259271 | |
dc.identifier.doi | 10.1007/s13555-024-01113-3 | |
dc.identifier.issn | 1396-0296 | |
dc.identifier.issn | 1529-8019 | |
dc.identifier.uri | https://hdl.handle.net/10037/34945 | |
dc.language.iso | eng | en_US |
dc.relation.journal | Dermatologic Therapy | |
dc.rights.holder | Copyright 2024 The Author(s) | en_US |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0 | en_US |
dc.rights | Attribution 4.0 International (CC BY 4.0) | en_US |
dc.title | Botulinum Toxin A and B for Palmoplantar Hyperhidrosis | en_US |
dc.type | Journal article | en_US |
dc.type | Tidsskriftartikkel | en_US |