Show simple item record

dc.contributor.authorDuelund-Jakobsen, Jakob
dc.contributor.authorBuntzen, Steen
dc.contributor.authorLundby, Lilli
dc.contributor.authorLaurberg, Søren
dc.contributor.authorSørensen, Michael
dc.contributor.authorRydningen, Mona Birgitte
dc.date.accessioned2024-10-15T07:21:53Z
dc.date.available2024-10-15T07:21:53Z
dc.date.issued2024-03-11
dc.description.abstractAim: Sacral neuromodulation (SNM) is approved for the treatment of faecal incontinence (FI) in a two-stage technique. With standardized implantation, approximately 90% of pa tients undergo successful Stage I operation and proceed to a permanent implant (Stage II). The aim of this work was to explore the feasibility of SNM as a one-stage procedure and report the 24-week efficacy.<p> <p>Method: This study included patients diagnosed with idiopathic FI or FI due to an external anal sphincter defect ≤160° and one or more episodes of FI per week despite maximal conservative therapy. Patients were offered a one-stage procedure if a motor response of the external anal sphincter was achieved in three or more poles with at least one at ≤1.5 mA at lead placement. Patients were followed for 24 weeks. Their evaluation included the Wexner/St Mark's Incontinence Score, Faecal Incontinence Quality of Life score (FIQoL), a visual analogue scale (VAS) for assessing patient satisfaction and a bowel habit diary. <p>Results: Seventy-three patients with a median age of 60 years (interquartile range 50–69 years) completed this prospective study. Episodes of FI were significantly reduced at the 24-week follow-up, from 13 (8–23) at baseline to 2 (0–5) (p-value = 0002). A ≥50% reduction in the number of FI episodes was achieved in 92% of participants. The Wexner score improved significantly from 16 (14–17) at baseline to 9 (5–13) (p-value < 0.001), and the St Mark's score improved significantly from 18 (16–20) to 11 (7–16) (p-value < 0.001). All domains in the FIQoL score and VAS for patient satisfaction improved significantly following the one-stage procedure. <p>Conclusion: A one-stage implantation procedure is feasible in selected patients with FI, significantly improving continence, quality of life and patient satisfaction after 24 weeks of follow-up.en_US
dc.identifier.citationDuelund-Jakobsen, Buntzen, Lundby, Laurberg, Sørensen, Rydningen. One-stage implant in sacral neuromodulation for faecal incontinence – short-term outcome from a prospective study. Colorectal Disease. 2024en_US
dc.identifier.cristinIDFRIDAID 2261995
dc.identifier.doi10.1111/codi.16936
dc.identifier.issn1462-8910
dc.identifier.issn1463-1318
dc.identifier.urihttps://hdl.handle.net/10037/35233
dc.language.isoengen_US
dc.publisherWileyen_US
dc.relation.journalColorectal Disease
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2024 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.rightsAttribution 4.0 International (CC BY 4.0)en_US
dc.titleOne-stage implant in sacral neuromodulation for faecal incontinence – short-term outcome from a prospective studyen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


File(s) in this item

Thumbnail

This item appears in the following collection(s)

Show simple item record

Attribution 4.0 International (CC BY 4.0)
Except where otherwise noted, this item's license is described as Attribution 4.0 International (CC BY 4.0)