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dc.contributor.authorTaxt, Arne Michael
dc.contributor.authorEldholm, Vegard
dc.contributor.authorKols, Nicola Isabelle
dc.contributor.authorHaugan, Maria Schei
dc.contributor.authorRaffelsberger, Niclas Peter
dc.contributor.authorAsfeldt, Anne Mette
dc.contributor.authorIngebretsen, André
dc.contributor.authorBlomfeldt, Anita
dc.contributor.authorKilhus, Kristin
dc.contributor.authorLindemann, Paul Christoffer
dc.contributor.authorBentele, Horst
dc.contributor.authorStålcrantz, Jeanette
dc.contributor.authorØdeskaug, Liz Ertzeid
dc.contributor.authorBerg, Thale Cathrine
dc.date.accessioned2025-05-16T10:44:52Z
dc.date.available2025-05-16T10:44:52Z
dc.date.issued2025-02-06
dc.description.abstractWe report a national outbreak of Serratia marcescens complex type 755 (ct755) in Norway, with 74 cases identified between June 2021 and February 2023. Careful reviews of patient journals and interviews were performed, involving 33 hospitals throughout Norway. All available clinical isolates of S. marcescens collected between January 2021 and February 2023 (n=455, including cases) from all involved hospitals were whole genome sequenced. Cases displayed a pattern of opportunistic infections, as usually observed with S. marcescens. No epidemiological links, common exposures or common risk factors were identified. The investigation pointed to an outbreak source present in the community. We suspect a nationally distributed product, possibly a food product, as the source. Phylogenetic analysis revealed a highly diverse bacterial population containing multiple distinct clusters. The outbreak cluster ct755 stands out as the largest and least diverse clone of a continuum, however a second cluster (ct281) also triggered a separate outbreak investigation. This report highlights challenges in the investigation of outbreaks caused by opportunistic pathogens and suggests that the presence of identical strains of S. marcescens in clinical samples is more common than previously recognised.en_US
dc.identifier.citationTaxt, Eldholm, Kols, Haugan, Raffelsberger, Asfeldt, Ingebretsen, Blomfeldt, Kilhus, Lindemann, Bentele, Stålcrantz, Ødeskaug, Berg. A national outbreak of Serratia marcescens complex: investigation reveals genomic population structure but no source, Norway, June 2021 to February 2023. Eurosurveillance. 2025en_US
dc.identifier.cristinIDFRIDAID 2379819
dc.identifier.doi10.2807/1560-7917.ES.2025.30.5.2400291
dc.identifier.issn1025-496X
dc.identifier.issn1560-7917
dc.identifier.urihttps://hdl.handle.net/10037/37094
dc.language.isoengen_US
dc.publisherEuropean Centre for Disease Prevention and Controlen_US
dc.relation.journalEurosurveillance
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2025 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.rightsAttribution 4.0 International (CC BY 4.0)en_US
dc.titleA national outbreak of Serratia marcescens complex: investigation reveals genomic population structure but no source, Norway, June 2021 to February 2023en_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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Attribution 4.0 International (CC BY 4.0)
Except where otherwise noted, this item's license is described as Attribution 4.0 International (CC BY 4.0)