Limitations of the anticancer drug product Taxotere® have encouraged researchers to entrap the active ingredient docetaxel (DTX) into nanocarriers such as liposomes. However, until now no DTX-liposome formulation has reached the clinic. Hence, in the present study, different Soy-PC based DTX-liposome formulations were screened in an attempt to identify lipid-compositions with promising DTX-entrapment ...

<p><b> Background</b> Light-curing of materials during restorative dental procedures poses a risk for pulp tissue overheating. Therefore, the aim of this study was to investigate the effect of indirect air-cooling on pulp chamber temperatures during light-curing of varying volume teeth and absence/presence of resin-based composite (RBC) at different exposure time. <p><b> Methods</b> The ...

This study aimed to compare the content of the Norwegian Kvello AF for child welfare investigations with similar frameworks from Sweden (BBIC) and Denmark (ICS). The comparison was based on detailed descriptions of each framework, retrieved from authorized websites, textbooks, manuals, course material, and, for the Kvello AF, also personal communication with the author. An ecological triangle model ...

The effect of birth weight and childhood body mass index (BMI) on adolescents’ bone parameters is not established. The aim of this longitudinal, population‐based study was to investigate the association of birth weight, childhood BMI, and growth, with adolescent bone mass and bone density in a sample of 633 adolescents (48% girls) from The Tromsø Study: Fit Futures. This population‐based cohort study ...

This thesis provides a wider insight and explores the multiple problems and challenges resettling refugees and other migrants do face settling in a new country. Pointing to the persistence of traumatic experiences at different levels and the high risk of diseases, the need for health services and care should be prioritized. However, the issue of language seems to be one of the major barriers refugees ...

Objectives: Studies on the dynamics between service organization and acute admissions to psychiatric specialized care have given ambiguous results. We studied the effect of several variables, including service organization, coercion, and patient characteristics on the rate of acute admissions to psychiatric specialist services. In a natural experiment-like study in Norway, we compared a ...

Background - Medical uncertainty is a pervasive and important problem, but the strategies physicians use to manage it have not been systematically described.<p> <p>Objectives - To explore the uncertainty management strategies employed by physicians practicing in acute-care hospital settings and to organize these strategies within a conceptual taxonomy that can guide further efforts to understand ...

Background: Tranexamic acid (TXA) reduces mortality in trauma patients. Intramuscular (IM) administration could be advantageous in low-resource and military settings. Achieving the same serum concentration as intravenous (IV) administration is important to achieve equal mortality reduction. Therefore, we aimed to investigate whether dividing an IM dose of TXA between two injection sites and whether ...

Procrastination is common among students, with prevalence estimates double or even triple those of the working population. This inflated prevalence indicates that the academic environment may appear as “procrastination friendly” to students. In the present paper, we identify social, cultural, organizational, and contextual factors that may foster or facilitate procrastination (such as large degree ...

Health care service provision of individualised treatment to an ageing population prone to chronic conditions and multimorbidities is threatened. There is a need for digitally supported care, that is, (1) person-centred, (2) integrated, and (3) proactive. The research project <i>3P, Patients and Professionals in Productive Teams</i>, aimed to validate and verify the prerequisites for health care ...